{"id":13427,"date":"2021-01-31T22:14:21","date_gmt":"2021-02-01T03:14:21","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetica-de-sars-coronavirus-infeccao-hamano-2005\/"},"modified":"2021-02-20T20:47:07","modified_gmt":"2021-02-21T01:47:07","slug":"genetica-de-sars-coronavirus-infeccao-hamano-2005","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-sars-coronavirus-infeccao-hamano-2005\/","title":{"rendered":"Infec\u00e7\u00e3o por coronav\u00edrus SARS (Hamano, 2005)"},"content":{"rendered":"\n

T\u00cdTULO DO ESTUDO:<\/strong> Polimorfismos de genes indut\u00edveis por interferon OAS-1 e MxA associados com SARS na popula\u00e7\u00e3o vietnamita<\/a><\/p>\n\n

RESUMO:<\/strong> Descoberta de uma variante gen\u00e9tica no gene OAS-1 associada ao aumento do risco de s\u00edndrome respirat\u00f3ria aguda grave (SARS) coronav\u00edrus<\/em> infec\u00e7\u00e3o.<\/p>\n\n

VIS\u00c3O GERAL:<\/strong> Em 2003, s\u00edndrome respirat\u00f3ria aguda grave (SARS) coronav\u00edrus<\/em> surgiu na China. Ele se espalhou para pa\u00edses da \u00c1sia, Europa e Am\u00e9rica do Norte, levando a um total de aproximadamente 8.000 casos. A SARS \u00e9 uma doen\u00e7a infecciosa que pode causar sintomas semelhantes aos da gripe, incluindo febre, tosse e falta de ar. Embora v\u00e1rios fatores de risco cl\u00ednicos para o desenvolvimento de SARS, como ter mais de 60 anos ou diabetes, tenham sido identificados, pouco se sabe sobre como a gen\u00e9tica afeta a suscetibilidade \u00e0 SARS coronav\u00edrus<\/em> infec\u00e7\u00e3o. Este estudo usou dados gen\u00e9ticos de 147 indiv\u00edduos vietnamitas, 60 dos quais eram pacientes com SARS, e descobriu uma variante gen\u00e9tica (rs2660) no gene OAS-1 que est\u00e1 associada \u00e0 suscetibilidade \u00e0 infec\u00e7\u00e3o com SARS coronav\u00edrus<\/em> . Especificamente, o alelo G da variante rs2660 foi associado ao aumento da suscetibilidade \u00e0 infec\u00e7\u00e3o com o SARS coronav\u00edrus<\/em> . (Observa\u00e7\u00e3o: este estudo n\u00e3o \u00e9 um estudo de associa\u00e7\u00e3o do genoma. Apenas algumas variantes foram genotipadas seletivamente.)<\/p>\n\n

VOC\u00ca SABIA?<\/strong> O v\u00edrus SARS-CoV que causou o surto de SARS em 2003 \u00e9 muito semelhante ao SARS-CoV-2, que \u00e9 respons\u00e1vel pela pandemia de doen\u00e7a coronav\u00edrus 2019 (COVID-19). [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE AMOSTRA:<\/strong> Saiba mais sobre o Nebula Research Library<\/a> . <\/p>\n\n

\"resultado<\/a><\/figure>\n\n

<\/p>\n\n

VARIANTES ANALISADAS:<\/strong> rs2660<\/p>\n\n

RECURSOS ADICIONAIS:<\/strong>S\u00edndrome respirat\u00f3ria aguda grave (SARS)<\/a>SARS: As pessoas que arriscaram suas vidas para deter o v\u00edrus<\/a><\/p>\n\n

ATUALIZA\u00c7\u00c3O SEMANAL:<\/strong> 23 de mar\u00e7o de 2020<\/p>\n\n

Para atualiza\u00e7\u00f5es sobre a gen\u00e9tica de COVID-19, visite: https:\/\/nebula.org\/blog\/category\/science\/<\/a><\/p>\n\n

Voc\u00ea pode aprender mais sobre testes caseiros de coronav\u00edrus<\/a> em nossa revis\u00e3o!<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DO ESTUDO: Polimorfismos de genes indut\u00edveis por interferon OAS-1 e MxA associados com SARS na popula\u00e7\u00e3o vietnamita RESUMO: Descoberta de uma variante gen\u00e9tica no gene OAS-1 associada ao aumento do risco de s\u00edndrome respirat\u00f3ria aguda grave (SARS) coronav\u00edrus infec\u00e7\u00e3o. …<\/p>\n

Infec\u00e7\u00e3o por coronav\u00edrus SARS (Hamano, 2005)<\/span> Leia mais \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":13429,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4999],"tags":[],"class_list":["post-13427","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports-pt-br"],"yoast_head":"\nA gen\u00e9tica da infec\u00e7\u00e3o por coronav\u00edrus SARS (Hamano, 2005)<\/title>\n<meta name=\"description\" content=\"Carregue seus dados de DNA, explore as variantes gen\u00e9ticas ligadas \u00e0 infec\u00e7\u00e3o por coronav\u00edrus SARS (Hamano, 2005) e descubra sua pontua\u00e7\u00e3o polig\u00eanica.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nebula.org\/blog\/pt-br\/genetica-de-sars-coronavirus-infeccao-hamano-2005\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A gen\u00e9tica da infec\u00e7\u00e3o por coronav\u00edrus SARS (Hamano, 2005)\" \/>\n<meta property=\"og:description\" content=\"Carregue seus dados de DNA, explore as variantes gen\u00e9ticas ligadas \u00e0 infec\u00e7\u00e3o por coronav\u00edrus SARS (Hamano, 2005) e descubra sua 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