{"id":13560,"date":"2021-01-31T22:14:52","date_gmt":"2021-02-01T03:14:52","guid":{"rendered":"https:\/\/nebula.org\/blog\/genetica-of-sars-coronavirus-infeccao-tu-2015\/"},"modified":"2021-02-20T20:29:48","modified_gmt":"2021-02-21T01:29:48","slug":"genetica-of-sars-coronavirus-infeccao-tu-2015","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/pt-br\/genetica-of-sars-coronavirus-infeccao-tu-2015\/","title":{"rendered":"Infec\u00e7\u00e3o por coronav\u00edrus SARS (Tu, 2015)"},"content":{"rendered":"\n

T\u00cdTULO DO ESTUDO:<\/strong> Polimorfismos funcionais do CCL2<\/em> e MBL<\/em> genes aumentam cumulativamente a suscetibilidade \u00e0 infec\u00e7\u00e3o por coronav\u00edrus com s\u00edndrome respirat\u00f3ria aguda grave<\/a><\/p>\n\n

RESUMO:<\/strong> Identifica\u00e7\u00e3o de 2 variantes gen\u00e9ticas associadas a um risco aumentado de s\u00edndrome respirat\u00f3ria aguda grave (SARS) coronav\u00edrus<\/em> infec\u00e7\u00e3o.<\/p>\n\n

VIS\u00c3O GERAL:<\/strong> S\u00edndrome respirat\u00f3ria aguda grave (SARS) coronav\u00edrus<\/em> surgiu em 2003 na China. Durante aquele ano, mais de 8.000 infec\u00e7\u00f5es em 26 pa\u00edses foram relatadas. Os sintomas da SARS s\u00e3o semelhantes aos da gripe e incluem febre e tosse seca. Casos graves s\u00e3o comuns e resultam em uma taxa de mortalidade de aproximadamente 10%. Este estudo examinou os dados gen\u00e9ticos de quase 1000 indiv\u00edduos de ascend\u00eancia chinesa que foram diagnosticados com SARS. O estudo identificou 2 variantes que est\u00e3o associadas \u00e0 suscetibilidade \u00e0 infec\u00e7\u00e3o com o SARS coronav\u00edrus<\/em> . Uma variante est\u00e1 no gene CCL2, que desempenha um papel na atra\u00e7\u00e3o macr\u00f3fagos<\/em> a um local de infec\u00e7\u00e3o. A outra variante est\u00e1 no gene MBL, que ajuda o sistema imunol\u00f3gico a reconhecer padr\u00f5es moleculares comumente encontrados na superf\u00edcie de muitos v\u00edrus e bact\u00e9rias. (Observa\u00e7\u00e3o: este estudo n\u00e3o \u00e9 um estudo de associa\u00e7\u00e3o do genoma. Apenas algumas variantes foram genotipadas seletivamente.)<\/p>\n\n

VOC\u00ca SABIA?<\/strong> O coronav\u00edrus SARS surgiu como resultado de uma transmiss\u00e3o de animal para humano. Acredita-se que o hospedeiro original tenha sido um morcego ou uma civeta, um animal parecido com um gato encontrado na \u00c1sia tropical. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE AMOSTRA:<\/strong> Saiba mais sobre o Nebula Research Library<\/a> . <\/p>\n\n

\"Relatório<\/a><\/figure>\n\n

<\/p>\n\n

VARIANTES ASSOCIADAS AO RISCO DE INFEC\u00c7\u00c3O POR SARS CORONAVIRUS:<\/strong> rs1024611, rs1800450<\/p>\n\n

RECURSOS ADICIONAIS:<\/strong>S\u00edndrome respirat\u00f3ria aguda grave (SARS)<\/a>Coronav\u00edrus SARS (V\u00eddeo)<\/a><\/p>\n\n

ATUALIZA\u00c7\u00c3O SEMANAL:<\/strong> 23 de mar\u00e7o de 2020<\/p>\n\n

Para atualiza\u00e7\u00f5es sobre a gen\u00e9tica de COVID-19, visite: https:\/\/nebula.org\/blog\/category\/science\/<\/a><\/p>\n\n

Voc\u00ea pode aprender mais sobre testes caseiros de coronav\u00edrus<\/a> em nossa revis\u00e3o!<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DO ESTUDO: Polimorfismos funcionais do CCL2 e MBL genes aumentam cumulativamente a suscetibilidade \u00e0 infec\u00e7\u00e3o por coronav\u00edrus com s\u00edndrome respirat\u00f3ria aguda grave RESUMO: Identifica\u00e7\u00e3o de 2 variantes gen\u00e9ticas associadas a um risco aumentado de s\u00edndrome respirat\u00f3ria aguda grave (SARS) …<\/p>\n

Infec\u00e7\u00e3o por coronav\u00edrus SARS (Tu, 2015)<\/span> Leia mais \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":13563,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4999],"tags":[],"class_list":["post-13560","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports-pt-br"],"yoast_head":"\nA gen\u00e9tica da infec\u00e7\u00e3o por Coronavirus SARS (Tu, 2015)<\/title>\n<meta name=\"description\" content=\"Carregue seus dados de DNA, explore as variantes gen\u00e9ticas ligadas ao risco de infec\u00e7\u00e3o por coronav\u00edrus SARS (Tu, 2015) e descubra sua pontua\u00e7\u00e3o polig\u00eanica.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nebula.org\/blog\/pt-br\/genetica-of-sars-coronavirus-infeccao-tu-2015\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A gen\u00e9tica da infec\u00e7\u00e3o por Coronavirus SARS (Tu, 2015)\" \/>\n<meta property=\"og:description\" content=\"Carregue seus dados de DNA, explore as variantes gen\u00e9ticas ligadas ao risco de infec\u00e7\u00e3o por coronav\u00edrus SARS (Tu, 2015) e descubra sua pontua\u00e7\u00e3o 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