{"id":13564,"date":"2021-01-31T22:14:54","date_gmt":"2021-02-01T03:14:54","guid":{"rendered":"https:\/\/nebula.org\/blog\/prolapso-de-orgao-pelvico-olafsdottir-2020\/"},"modified":"2021-02-20T20:32:38","modified_gmt":"2021-02-21T01:32:38","slug":"prolapso-de-orgao-pelvico-olafsdottir-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/pt-br\/prolapso-de-orgao-pelvico-olafsdottir-2020\/","title":{"rendered":"Prolapso de \u00f3rg\u00e3o p\u00e9lvico (Olafsdottir, 2020)"},"content":{"rendered":"\n

T\u00cdTULO DO ESTUDO:<\/strong> A associa\u00e7\u00e3o do genoma identifica sete loci para prolapso de \u00f3rg\u00e3o p\u00e9lvico na Isl\u00e2ndia e no Reino Unido<\/a><\/p>\n\n

RESUMO:<\/strong> Identifica\u00e7\u00e3o de 8 variantes gen\u00e9ticas associadas ao prolapso de \u00f3rg\u00e3os p\u00e9lvicos.<\/p>\n\n

VIS\u00c3O GERAL:<\/strong> Os m\u00fasculos que sustentam os \u00f3rg\u00e3os p\u00e9lvicos de uma mulher podem enfraquecer, fazendo com que \u00f3rg\u00e3os como a bexiga e o \u00fatero caiam no p\u00e9lvis<\/em> . Essa condi\u00e7\u00e3o \u00e9 chamada de prolapso de \u00f3rg\u00e3o p\u00e9lvico, que resulta em sintomas como press\u00e3o na regi\u00e3o p\u00e9lvica, problemas intestinais e disfun\u00e7\u00e3o sexual. \u00c9 muito comum, afetando quase 1 em cada 3 mulheres em algum momento da vida. Este estudo de associa\u00e7\u00e3o do genoma examinou mais de 355.000 mulheres de ascend\u00eancia europeia para entender melhor os fatores de risco gen\u00e9ticos para prolapso de \u00f3rg\u00e3os p\u00e9lvicos. O estudo identificou 8 variantes associadas ao prolapso de \u00f3rg\u00e3os p\u00e9lvicos, que coletivamente explicam cerca de 12% da hereditariedade da condi\u00e7\u00e3o. Uma das variantes gen\u00e9ticas descobertas parece afetar o estrog\u00eanio<\/em> via de sinaliza\u00e7\u00e3o, enquanto outra variante influencia a manuten\u00e7\u00e3o do tecido conjuntivo no p\u00e9lvis<\/em> .<\/p>\n\n

VOC\u00ca SABIA?<\/strong> O prolapso de \u00f3rg\u00e3os p\u00e9lvicos \u00e9 mais comumente causado pela gravidez e pelo parto. Obesidade, idade avan\u00e7ada e condi\u00e7\u00f5es com tosse frequente tamb\u00e9m s\u00e3o fatores de risco para o desenvolvimento da doen\u00e7a. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE AMOSTRA:<\/strong> Saiba mais sobre o Nebula Research Library<\/a> . <\/p>\n\n

\"Resultados<\/a><\/figure>\n\n

VARIANTES ANALISADAS:<\/strong> rs3820282 rs9306894 rs1430191 rs3791675 rs7682992 rs72624976 rs1247943 rs12325192<\/p>\n\n

RECURSOS ADICIONAIS:<\/strong>Prolapso p\u00e9lvico<\/a>Estrog\u00eanio<\/a> <\/a>V\u00eddeo<\/a><\/p>\n\n

ATUALIZA\u00c7\u00c3O SEMANAL:<\/strong> 31 de mar\u00e7o de 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DO ESTUDO: A associa\u00e7\u00e3o do genoma identifica sete loci para prolapso de \u00f3rg\u00e3o p\u00e9lvico na Isl\u00e2ndia e no Reino Unido RESUMO: Identifica\u00e7\u00e3o de 8 variantes gen\u00e9ticas associadas ao prolapso de \u00f3rg\u00e3os p\u00e9lvicos. VIS\u00c3O GERAL: Os m\u00fasculos que sustentam os …<\/p>\n

Prolapso de \u00f3rg\u00e3o p\u00e9lvico (Olafsdottir, 2020)<\/span> Leia mais \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":13568,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4999],"tags":[],"class_list":["post-13564","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports-pt-br"],"yoast_head":"\nA 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