{"id":13574,"date":"2021-01-31T22:14:58","date_gmt":"2021-02-01T03:14:58","guid":{"rendered":"https:\/\/nebula.org\/blog\/espessura-do-cortex-cerebral-grasby-2020-2\/"},"modified":"2021-02-20T20:49:12","modified_gmt":"2021-02-21T01:49:12","slug":"espessura-do-cortex-cerebral-grasby-2020-2","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/pt-br\/espessura-do-cortex-cerebral-grasby-2020-2\/","title":{"rendered":"Espessura do c\u00f3rtex cerebral (Grasby, 2020)"},"content":{"rendered":"\n

T\u00cdTULO DO ESTUDO:<\/strong> A arquitetura gen\u00e9tica do c\u00f3rtex cerebral humano<\/a><\/p>\n\n

RESUMO:<\/strong> Identifica\u00e7\u00e3o de 27 regi\u00f5es gen\u00e9ticas associadas \u00e0 espessura cortical.<\/p>\n\n

VIS\u00c3O GERAL:<\/strong> o c\u00f3rtex cerebral<\/em> \u00e9 a camada externa do c\u00e9rebro respons\u00e1vel por tarefas cognitivas, como percep\u00e7\u00e3o, pensamento e mem\u00f3ria. Acredita-se que o c\u00f3rtex espesso do c\u00e9rebro humano tenha evolu\u00eddo para cumprir essas fun\u00e7\u00f5es. Para identificar variantes gen\u00e9ticas associadas \u00e0 espessura cortical, este estudo combinou dados gen\u00e9ticos com dados de imagens cerebrais de mais de 50.000 indiv\u00edduos. O estudo identificou 27 regi\u00f5es gen\u00e9ticas, que explicam cerca de 26% da herdabilidade da espessura cortical. Estas regi\u00f5es est\u00e3o pr\u00f3ximas de genes que codificam receptores de laminina que est\u00e3o implicados em neuronal<\/em> diferencia\u00e7\u00e3o e migra\u00e7\u00e3o celular.<\/p>\n\n

VOC\u00ca SABIA?<\/strong> \u201cCabe\u00e7a-dura\u201d \u00e9 um termo impr\u00f3prio. Embora “cabe\u00e7a dura” normalmente se refira a uma pessoa que n\u00e3o \u00e9 inteligente, alguns estudos de neuroimagem indicam que a intelig\u00eancia est\u00e1 positivamente correlacionada com a espessura cortical durante a primeira inf\u00e2ncia. [SOURCE]<\/a><\/p>\n\n

RESULTADOS DE AMOSTRA:<\/strong> Saiba mais sobre o Nebula Research Library<\/a> . <\/p>\n\n

\"Resultados<\/a><\/figure>\n\n

VARIANTES ANALISADAS:<\/strong> rs71471500 rs10851383 rs62002282 rs56023709 rs149142 rs533577 rs2316766 rs11692435 rs117461235 rs62115964 rs117461235 rs4955920 rs11386753 rs35021943 rs4823878 rs160459 rs10495963 rs1822105 rs3847803 rs73215353 rs7824177 rs12058942 rs4572176 rs11745941 rs12110247 rs9537915 rs12764880<\/p>\n\n

RECURSOS ADICIONAIS:<\/strong>V\u00eddeo<\/a>Espessura cerebral<\/a><\/p>\n\n

ATUALIZA\u00c7\u00c3O SEMANAL:<\/strong> 31 de mar\u00e7o de 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00cdTULO DO ESTUDO: A arquitetura gen\u00e9tica do c\u00f3rtex cerebral humano RESUMO: Identifica\u00e7\u00e3o de 27 regi\u00f5es gen\u00e9ticas associadas \u00e0 espessura cortical. VIS\u00c3O GERAL: o c\u00f3rtex cerebral \u00e9 a camada externa do c\u00e9rebro respons\u00e1vel por tarefas cognitivas, como percep\u00e7\u00e3o, pensamento e mem\u00f3ria. …<\/p>\n

Espessura do c\u00f3rtex cerebral (Grasby, 2020)<\/span> Leia mais \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":13567,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[4999],"tags":[],"class_list":["post-13574","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports-pt-br"],"yoast_head":"\nOs 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