{"id":1244,"date":"2020-04-06T12:00:00","date_gmt":"2020-04-06T16:00:00","guid":{"rendered":"https:\/\/nebula.org\/blog\/?p=1244"},"modified":"2021-01-27T01:56:11","modified_gmt":"2021-01-27T06:56:11","slug":"genetics-of-handedness-wiberg-2009","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/genetics-of-handedness-wiberg-2009\/","title":{"rendered":"Handedness (Wiberg, 2009)"},"content":{"rendered":"\n<p><strong>STUDY TITLE: <\/strong><a href=\"https:\/\/academic.oup.com\/brain\/article\/142\/10\/2938\/5556832\">Handedness, language areas and neuropsychiatric diseases: insights from brain imaging and genetics<\/a><\/p>\n\n\n\n<p><strong>SUMMARY:<\/strong> Identification of 4 novel genetic variants correlated with handedness. <\/p>\n\n\n\n<p><strong>DESCRIPTION: <\/strong>Are you a righty or a lefty? Nearly 90% of individuals are right-handed. While your dominant hand appears to be hereditary, the genetics that determines this is poorly understood. This genome-wide association study of nearly 400,000 individuals of European ancestry identified 4 novel genetic variants correlated to handedness. These variants help explain ~1% of the heritability of your dominant hand. Of these, 3 are in or near genes that play a role in the development and organization of the brain, specifically the areas that process language. The discovered variants are also associated with multiple psychiatric and neurodegenerative conditions, including Parkinson&#8217;s disease and schizophrenia.<\/p>\n\n\n\n<p><strong>DID YOU KNOW?<\/strong> The skew of right-handed individuals is unique to humans! While some animals seem to prefer using one hand (or leg or paw) over the other, the ratio is nearly always 50-50. [<a href=\"https:\/\/www.kidney.org\/atoz\/content\/kidneystones_prevent\">SOURCE<\/a>]<\/p>\n\n\n\n<p><strong>SAMPLE RESULTS:<\/strong> Learn more about the<a href=\"https:\/\/nebula.org\/blog\/nebula-library-unlocking-genetic-research\/\"> Nebula Research Library<\/a>.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/nebula.org\/free-dna-upload-analysis\/\"><img decoding=\"async\" src=\"http:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/Nebula-personalized-results-genomics-1024x375.png\" alt=\"This image has an empty alt attribute; its file name is Nebula-personalized-results-genomics-1024x375.png\"\/><\/a><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>HANDEDNESS-ASSOCIATED VARIANTS:<\/strong> rs199512, rs45608532, rs3094128, rs13017199<\/p>\n\n\n\n<p><strong>ADDITIONAL RESOURCES:<\/strong> <br><a rel=\"noreferrer noopener\" href=\"https:\/\/www.youtube.com\/watch?v=NPvMUpcxPSA\" target=\"_blank\">Handedness (Video)<\/a><br><a rel=\"noreferrer noopener\" href=\"https:\/\/en.wikipedia.org\/wiki\/Neuroanatomy_of_handedness\" target=\"_blank\">Neuroanatomy of Handedness<\/a><\/p>\n\n\n\n<p><strong>WEEKLY UPDATE:<\/strong> September 12, 2019<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><br><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><br><br><\/p>\n\n\n\n<p><br><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><br><\/p>\n\n\n\n<p><br><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>STUDY TITLE: Handedness, language areas and neuropsychiatric diseases: insights from brain imaging and genetics SUMMARY: Identification of 4 novel genetic variants correlated with handedness. DESCRIPTION: Are you a righty or a lefty? Nearly 90% of individuals are right-handed. While your &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"ast-button\" href=\"https:\/\/nebula.org\/blog\/genetics-of-handedness-wiberg-2009\/\"> <span class=\"screen-reader-text\">Handedness (Wiberg, 2009)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":1245,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[50],"tags":[],"class_list":["post-1244","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports"],"yoast_head":"<!-- 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content=\"https:\/\/nebula.org\/blog\/genetics-of-handedness-wiberg-2009\/\" \/>\n<meta property=\"og:site_name\" content=\"Nebula Genomics Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/facebook.com\/nebulagenomics\" \/>\n<meta property=\"article:published_time\" content=\"2020-04-06T16:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-01-27T06:56:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/02\/serge-kutuzov-H7srcJh4hF8-unsplash-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"739\" \/>\n\t<meta property=\"og:image:height\" content=\"924\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Garrett Dunlap, B.S.\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:site\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Garrett Dunlap, B.S.\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/nebula.org\/blog\/genetics-of-handedness-wiberg-2009\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/nebula.org\/blog\/genetics-of-handedness-wiberg-2009\/\"},\"author\":{\"name\":\"Garrett Dunlap, B.S.\",\"@id\":\"https:\/\/nebula.org\/blog\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e\"},\"headline\":\"Handedness (Wiberg, 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