{"id":1292,"date":"2020-03-29T00:00:58","date_gmt":"2020-03-29T04:00:58","guid":{"rendered":"https:\/\/nebula.org\/blog\/?p=1292"},"modified":"2021-01-27T01:56:13","modified_gmt":"2021-01-27T06:56:13","slug":"genetics-of-subcortical-brain-structures-hilbar-2015","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/","title":{"rendered":"Subcortical Brain Structures (Hilbar, 2015)"},"content":{"rendered":"\n

STUDY TITLE:<\/strong> Common genetic variants influence human subcortical brain structures<\/a><\/p>\n\n\n\n

SUMMARY:<\/strong> This study identified novel genetic variants that may influence the subcortical brain structures which are involved in complex activities including movement, emotions, and learning.<\/p>\n\n\n\n

DESCRIPTION: \u00a0<\/strong>The subcortical region consists of structures located below the outer layer of the brain. These structures have functions related to regulation of movement, learning, memory, and motivation. In this study, the volume of the brain structures of 30,717 individuals was measured using Magnetic Resonance Imaging (MRI). The study identified associations between genetic variants and the volume of different subcortical structures. The strongest associations were found near developmental genes that regulate apoptosis (programmed cell death) and the growth of neurons. This discovery provides insight into the causes of variability in human brain development.<\/p>\n\n\n\n

DID YOU KNOW?<\/strong> You can increase mental acuity by continuously learning new things, maintaining a healthy lifestyle, socializing, and sleeping well. [SOURCE<\/a>]<\/p>\n\n\n\n

SAMPLE RESULTS:<\/strong> Learn more about the Nebula Research Library<\/a>.<\/p>\n\n\n\n

\"Subcortical<\/a><\/figure>\n\n\n\n

BRAIN STRUCTURE-ASSOCIATED VARIANTS: <\/strong>rs945270, rs77956314, rs62097986, rs6087771, rs683250, rs61921502, rs1318862<\/p>\n\n\n\n

ADDITIONAL RESOURCES:<\/strong>
Subcortical Structures<\/a>
Early Brain Development<\/a><\/p>\n\n\n\n

WEEKLY UPDATE:<\/strong> July 26, 2019<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDY TITLE: Common genetic variants influence human subcortical brain structures SUMMARY: This study identified novel genetic variants that may influence the subcortical brain structures which are involved in complex activities including movement, emotions, and learning. DESCRIPTION: \u00a0The subcortical region consists …<\/p>\n

Subcortical Brain Structures (Hilbar, 2015)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":1293,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[50],"tags":[],"class_list":["post-1292","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports"],"yoast_head":"\nThe genetics of subcortical brain structures (Hilbrar, 2015)<\/title>\n<meta name=\"description\" content=\"This study identified novel genetic variants that may influence the subcortical brain structures. They are involved in movement, emotions, and learning.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The genetics of subcortical brain structures (Hilbrar, 2015)\" \/>\n<meta property=\"og:description\" content=\"This study identified novel genetic variants that may influence the subcortical brain structures. They are involved in movement, emotions, and learning.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/\" \/>\n<meta property=\"og:site_name\" content=\"Nebula Genomics Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/facebook.com\/nebulagenomics\" \/>\n<meta property=\"article:published_time\" content=\"2020-03-29T04:00:58+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-01-27T06:56:13+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/02\/brain_circuit_creative_subcortical.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"924\" \/>\n\t<meta property=\"og:image:height\" content=\"578\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Garrett Dunlap, B.S.\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/pancreatic_cancer_iv_bag-scaled.jpg\" \/>\n<meta name=\"twitter:creator\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:site\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Garrett Dunlap, B.S.\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/\"},\"author\":{\"name\":\"Garrett Dunlap, B.S.\",\"@id\":\"https:\/\/nebula.org\/blog\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e\"},\"headline\":\"Subcortical Brain Structures (Hilbar, 2015)\",\"datePublished\":\"2020-03-29T04:00:58+00:00\",\"dateModified\":\"2021-01-27T06:56:13+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/\"},\"wordCount\":182,\"publisher\":{\"@id\":\"https:\/\/nebula.org\/blog\/#organization\"},\"articleSection\":[\"Reports\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/\",\"url\":\"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/\",\"name\":\"The genetics of subcortical brain structures (Hilbrar, 2015)\",\"isPartOf\":{\"@id\":\"https:\/\/nebula.org\/blog\/#website\"},\"datePublished\":\"2020-03-29T04:00:58+00:00\",\"dateModified\":\"2021-01-27T06:56:13+00:00\",\"description\":\"This study identified novel genetic variants that may influence the subcortical brain structures. They are involved in movement, emotions, and learning.\",\"breadcrumb\":{\"@id\":\"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/nebula.org\/blog\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Subcortical Brain Structures (Hilbar, 2015)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/nebula.org\/blog\/#website\",\"url\":\"https:\/\/nebula.org\/blog\/\",\"name\":\"Nebula Genomics Blog\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/nebula.org\/blog\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/nebula.org\/blog\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/nebula.org\/blog\/#organization\",\"name\":\"Nebula Genomics\",\"url\":\"https:\/\/nebula.org\/blog\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/nebula.org\/blog\/#\/schema\/logo\/image\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Nebula Genomics\"},\"image\":{\"@id\":\"https:\/\/nebula.org\/blog\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/facebook.com\/nebulagenomics\",\"https:\/\/twitter.com\/nebulagenomics\",\"https:\/\/www.instagram.com\/nebulagenomics\/\",\"https:\/\/www.linkedin.com\/company\/nebula-genomics\/\",\"https:\/\/en.wikipedia.org\/wiki\/Nebula_Genomics\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/nebula.org\/blog\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e\",\"name\":\"Garrett Dunlap, B.S.\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/nebula.org\/blog\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g\",\"caption\":\"Garrett Dunlap, B.S.\"},\"description\":\"Garrett Dunlap earned a B.S. in Biology from Case Western Reserve University with a minor in Political Science. He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University.\u00a0He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.\",\"sameAs\":[\"https:\/\/nebula.org\/whole-genome-sequencing\/\"],\"url\":\"https:\/\/nebula.org\/blog\/author\/garrett-dunlap\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"The genetics of subcortical brain structures (Hilbrar, 2015)","description":"This study identified novel genetic variants that may influence the subcortical brain structures. They are involved in movement, emotions, and learning.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/","og_locale":"en_US","og_type":"article","og_title":"The genetics of subcortical brain structures (Hilbrar, 2015)","og_description":"This study identified novel genetic variants that may influence the subcortical brain structures. They are involved in movement, emotions, and learning.","og_url":"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/","og_site_name":"Nebula Genomics Blog","article_publisher":"https:\/\/facebook.com\/nebulagenomics","article_published_time":"2020-03-29T04:00:58+00:00","article_modified_time":"2021-01-27T06:56:13+00:00","og_image":[{"width":924,"height":578,"url":"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/02\/brain_circuit_creative_subcortical.jpg","type":"image\/jpeg"}],"author":"Garrett Dunlap, B.S.","twitter_card":"summary_large_image","twitter_image":"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/01\/pancreatic_cancer_iv_bag-scaled.jpg","twitter_creator":"@nebulagenomics","twitter_site":"@nebulagenomics","twitter_misc":{"Written by":"Garrett Dunlap, B.S.","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/#article","isPartOf":{"@id":"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/"},"author":{"name":"Garrett Dunlap, B.S.","@id":"https:\/\/nebula.org\/blog\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e"},"headline":"Subcortical Brain Structures (Hilbar, 2015)","datePublished":"2020-03-29T04:00:58+00:00","dateModified":"2021-01-27T06:56:13+00:00","mainEntityOfPage":{"@id":"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/"},"wordCount":182,"publisher":{"@id":"https:\/\/nebula.org\/blog\/#organization"},"articleSection":["Reports"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/","url":"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/","name":"The genetics of subcortical brain structures (Hilbrar, 2015)","isPartOf":{"@id":"https:\/\/nebula.org\/blog\/#website"},"datePublished":"2020-03-29T04:00:58+00:00","dateModified":"2021-01-27T06:56:13+00:00","description":"This study identified novel genetic variants that may influence the subcortical brain structures. They are involved in movement, emotions, and learning.","breadcrumb":{"@id":"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/nebula.org\/blog\/genetics-of-subcortical-brain-structures-hilbar-2015\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/nebula.org\/blog\/"},{"@type":"ListItem","position":2,"name":"Subcortical Brain Structures (Hilbar, 2015)"}]},{"@type":"WebSite","@id":"https:\/\/nebula.org\/blog\/#website","url":"https:\/\/nebula.org\/blog\/","name":"Nebula Genomics Blog","description":"","publisher":{"@id":"https:\/\/nebula.org\/blog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/nebula.org\/blog\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/nebula.org\/blog\/#organization","name":"Nebula Genomics","url":"https:\/\/nebula.org\/blog\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/nebula.org\/blog\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Nebula Genomics"},"image":{"@id":"https:\/\/nebula.org\/blog\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/facebook.com\/nebulagenomics","https:\/\/twitter.com\/nebulagenomics","https:\/\/www.instagram.com\/nebulagenomics\/","https:\/\/www.linkedin.com\/company\/nebula-genomics\/","https:\/\/en.wikipedia.org\/wiki\/Nebula_Genomics"]},{"@type":"Person","@id":"https:\/\/nebula.org\/blog\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e","name":"Garrett Dunlap, B.S.","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/nebula.org\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g","caption":"Garrett Dunlap, B.S."},"description":"Garrett Dunlap earned a B.S. in Biology from Case Western Reserve University with a minor in Political Science. He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University.\u00a0He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.","sameAs":["https:\/\/nebula.org\/whole-genome-sequencing\/"],"url":"https:\/\/nebula.org\/blog\/author\/garrett-dunlap\/"}]}},"_links":{"self":[{"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/posts\/1292","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/comments?post=1292"}],"version-history":[{"count":0,"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/posts\/1292\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/media\/1293"}],"wp:attachment":[{"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/media?parent=1292"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/categories?post=1292"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/tags?post=1292"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}