{"id":1843,"date":"2023-03-21T04:53:00","date_gmt":"2023-03-21T08:53:00","guid":{"rendered":"https:\/\/nebula.org\/blog\/?p=1843"},"modified":"2024-05-07T16:07:07","modified_gmt":"2024-05-07T20:07:07","slug":"is-eczema-genetic","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/is-eczema-genetic\/","title":{"rendered":"Atopic dermatitis &#8211; Is Eczema Genetic?"},"content":{"rendered":"\n<div class=\"wp-block-yoast-seo-table-of-contents yoast-table-of-contents\"><h2>Table of contents<\/h2><ul><li><a href=\"#h-nebula-genomics-dna-report-for-eczema\" data-level=\"2\">Nebula Genomics DNA Report for Eczema<\/a><\/li><li><a href=\"#h-what-is-eczema\" data-level=\"2\">What is Eczema?<\/a><\/li><li><a href=\"#h-is-eczema-a-genetic-disease\" data-level=\"2\">Is Eczema a Genetic Disease?<\/a><\/li><li><a href=\"#h-current-research-on-eczema\" data-level=\"2\">Current Research on Eczema<\/a><\/li><li><a href=\"#h-epidemiology\" data-level=\"2\">Epidemiology<\/a><\/li><li><a href=\"#h-symptoms\" data-level=\"2\">Symptoms<\/a><\/li><li><a href=\"#h-causes\" data-level=\"2\">Causes<\/a><\/li><li><a href=\"#h-diagnosis\" data-level=\"2\">Diagnosis<\/a><\/li><li><a href=\"#h-treatment\" data-level=\"2\">Treatment<\/a><ul><li><a href=\"#h-medications\" data-level=\"3\">Medications<\/a><\/li><li><a href=\"#h-light-therapy\" data-level=\"3\">Light therapy<\/a><\/li><li><a href=\"#h-infants-and-young-children\" data-level=\"3\">Infants and young children<\/a><\/li><\/ul><\/li><\/ul><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-nebula-genomics-dna-report-for-eczema\"><strong>Nebula Genomics DNA Report for Eczema<\/strong><\/h2>\n\n\n\n<p>Is eczema genetic? We created a DNA report based on a study that attempted to answer this question. Below you can see a SAMPLE DNA report. To get your personalized DNA report, purchase our <a href=\"https:\/\/nebula.org\/whole-genome-sequencing\/\">Whole Genome Sequencing<\/a>!<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img decoding=\"async\" width=\"886\" height=\"512\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2024\/05\/Screenshot-2024-05-07-at-2.30.10\u202fPM.png\" alt=\"\" class=\"wp-image-45678\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2024\/05\/Screenshot-2024-05-07-at-2.30.10\u202fPM.png 886w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2024\/05\/Screenshot-2024-05-07-at-2.30.10\u202fPM-300x173.png 300w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2024\/05\/Screenshot-2024-05-07-at-2.30.10\u202fPM-768x444.png 768w\" sizes=\"(max-width: 886px) 100vw, 886px\" \/><\/figure>\n\n\n\n<div class=\"wp-block-buttons aligncenter is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button aligncenter\"><a class=\"wp-block-button__link has-white-color has-vivid-cyan-blue-background-color has-text-color has-background wp-element-button\" href=\"https:\/\/nebula.org\/whole-genome-sequencing\/\" rel=\"https:\/\/nebula.org\/whole-genome-sequencing\/\"><strong>Sequence your genome and access over 200 DNA reports!<\/strong><\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-what-is-eczema\"><strong>What is Eczema?<\/strong><\/h2>\n\n\n\n<p>Dermatitis is the general term for any type of skin irritation. Eczema, or atopic dermatitis, is a long-term type of inflamed skin characterized by dry, itchy skin that may also appear red and swollen or weep clear fluid. Atopic eczema is not contagious.&nbsp;<\/p>\n\n\n\n<p>Atopic dermatitis is the most common type of eczema. Other forms include contact dermatitis, dyshidrotic eczema, nummular eczema, seborrheic dermatitis, and stasis dermatitis.<\/p>\n\n\n\n<p>Eczema is an autoimmune disease turned on when an allergen from outside of the body turns on the immune system, attacking healthy cells. As a result, the affected cells become inflamed, which leads to the dry, itchy skin that characterizes the condition.&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img decoding=\"async\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2023\/03\/eczema_sleeves-819x1024.jpg\" alt=\"Eczema on the arms, wrists, and hands\" class=\"wp-image-39100\" style=\"width:614px;height:768px\" width=\"614\" height=\"768\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2023\/03\/eczema_sleeves.jpg 739w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2023\/03\/eczema_sleeves-240x300.jpg 240w\" sizes=\"(max-width: 614px) 100vw, 614px\" \/><figcaption class=\"wp-element-caption\">Eczema on the arms, wrists, and hands. Heidi Akselin via <a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:TSW_eczema_sleeves.jpg\" target=\"_blank\" rel=\"noreferrer noopener\">Wikipedia<\/a>. CC-<a href=\"https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/deed.en\" target=\"_blank\" rel=\"noreferrer noopener\">Attribution-Share Alike 4.0 International<\/a>.<\/figcaption><\/figure>\n\n\n\n<p>Although it can appear at any time, the condition normally begins in childhood and changes in appearance depending on age. It is most common on most of the body during infancy (less than one year of age). <\/p>\n\n\n\n<p>This includes the face, scalp, hands, and feet. In adolescents, the knees and elbows are most affected. In adults, the rash tends to affect the neck and eyelids as well as knees and elbows.&nbsp;<\/p>\n\n\n\n<p>It can be very common in infants, but children may see significant improvement with age.&nbsp;<\/p>\n\n\n\n<p>Although there is no cure for the condition, there are multiple treatment options. Most treatments involve a topical application to ease symptoms and reduce <a href=\"https:\/\/nebula.org\/blog\/are-inflammatory-markers-genetic\/\">inflammation<\/a> of the skin.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-is-eczema-a-genetic-disease\"><strong>Is Eczema a Genetic Disease?<\/strong><\/h2>\n\n\n\n<p>In most cases, the <a href=\"https:\/\/medlineplus.gov\/genetics\/condition\/atopic-dermatitis\/#causes\" target=\"_blank\" rel=\"noreferrer noopener\">interaction of several genes<\/a> causes the condition, in addition to an environmental trigger. In rare cases, a single genetic variation for eczema appears to be the leading cause.<\/p>\n\n\n\n<p><strong>CARD11:<\/strong> This gene codes for a protein that turns on signaling pathways involved in the development and function of lymphocytes in the immune system. When this gene is mutated, T cells, which protect the body from infection, do not function properly. Specifically, they do not respond as strongly to foreign invaders and thus weaken the immune system and result in frequent infections.<\/p>\n\n\n\n<p>Although experts believe several genes are involved, each only contributes a small genetic risk of developing atopic eczema. They have linked the strongest association to a genetic mutation that affects the skin\u2019s ability to form a healthy protective barrier against allergic reactions and irritants.&nbsp;<\/p>\n\n\n\n<p><strong>FLG:<\/strong> This gene is mutated in 20 to 30 percent of people with the condition compared with 8 to 10 percent of the general population. It codes for a protein called profilaggrin, an essential component of the outer skin. The skin is a barrier that keeps water in and foreign substances like toxins, bacteria, and allergens out.&nbsp;<\/p>\n\n\n\n<p>When this gene is abnormal, the profilaggrin tends to be too short, an effect that reduces the protein\u2019s ability to create additional structures in the skin. Without a strong barrier, experts believe that allergens enter the skin and trigger the inflammatory response observed in the condition.&nbsp;<\/p>\n\n\n\n<p>Since not everyone with an FLG mutation develops genetic eczema, environmental conditions most likely play a role as well.<\/p>\n\n\n\n<p>Other genetic factors probably play a role in the skin barrier or the immune system.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-current-research-on-eczema\"><strong>Current Research on Eczema<\/strong><\/h2>\n\n\n\n<p>Eczema has become the topic of study of many institutions, and a lot has been discovered so far. This <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28826773\/\" target=\"_blank\" rel=\"noreferrer noopener\">2018 study<\/a> sheds light on genetic studies that have tried to identify the genes responsible for several conditions, eczema included. Two years before that, scientists had tapped into the <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26385242\/\" target=\"_blank\" rel=\"noreferrer noopener\">genetics and epigenetics of atopic dermatitis<\/a>.&nbsp;<\/p>\n\n\n\n<p>This exhaustive study goes deeper into <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5664152\/\" target=\"_blank\" rel=\"noreferrer noopener\">germline hypomorphic CARD11 mutations in severe atopic disease<\/a>. Eight patients with novel heterozygous mutations in CARD11 underwent a series of tests to determine the relationship between eczema and the type of genetic mutation associated with it.&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<p>Topical treatments like emollients and moisturizers have proven certain effectiveness at controlling eczema and preventing eczema flares. This <a href=\"https:\/\/www.cochrane.org\/CD012119\/SKIN_emollients-and-moisturisers-eczema\" target=\"_blank\" rel=\"noreferrer noopener\">2020 study<\/a> has mixed results based on subject experience about how well moisturizers help diminish pesky eczema symptoms.&nbsp;<\/p>\n\n\n\n<p>On the other hand, a Cochrane Library assessment of the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6517242\/\" target=\"_blank\" rel=\"noreferrer noopener\">effects of probiotics for the treatment of eczema<\/a> proved that their use makes little difference in patients. Therefore, they conclude that the use of probiotics is not based on evidence.&nbsp;<\/p>\n\n\n\n<p><br>Patients in general claim to suffer from mild eczema on hands, and others might perceive it as severe. There really isn\u2019t a metric to classify the severity of hand eczema. However, these authors devised a <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21658054\/\" target=\"_blank\" rel=\"noreferrer noopener\">classification based on the guideline of the Danish Contact Dermatitis Group<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-epidemiology\"><strong>Epidemiology<\/strong><\/h2>\n\n\n\n<p>According to the <a href=\"https:\/\/allergyasthmanetwork.org\/what-is-eczema\/eczema-statistics\/\" target=\"_blank\" rel=\"noreferrer noopener\">Allergy and Asthma Network<\/a>, eczema affects 31.6 million people in the United States. Out of that number, 18 million people have atopic dermatitis (AD), including 9.6 million children.&nbsp;<\/p>\n\n\n\n<p>Globally, 15-20% of children and 1-3% of adults are thought to have AD.&nbsp;<\/p>\n\n\n\n<p>The condition appears to affect male and female children to the same extent, but more female adults have it overall than males. It tends to affect people of all races and nationalities, although the risk appears to be smaller in children of Hispanic descent than those of other races.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-symptoms\"><strong>Symptoms<\/strong><\/h2>\n\n\n\n<p>The symptoms of eczema are different for each patient. You may even observe different signs on different parts of your body.&nbsp;<\/p>\n\n\n\n<p>The American Academy of Dermatology Association summarizes the symptoms by age on their website. A common symptom is itchy skin, which can range from mild to severe and often worsens at night, reducing sleep and negatively impacting quality of life. Scratching tends to make the skin conditions worse. Other symptoms to look for include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Dry, sensitive skin<\/li>\n\n\n\n<li>Inflamed, discolored skin<\/li>\n\n\n\n<li>Rough, leathery, or scaly patches of skin<\/li>\n\n\n\n<li>Oozing or crusting<\/li>\n\n\n\n<li>Areas of swelling<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img decoding=\"async\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2023\/03\/eczema-symptoms.png\" alt=\"Redness, blisters, and flaking\" class=\"wp-image-39108\" style=\"width:768px;height:512px\" width=\"768\" height=\"512\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2023\/03\/eczema-symptoms.png 924w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2023\/03\/eczema-symptoms-300x200.png 300w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2023\/03\/eczema-symptoms-768x512.png 768w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/><figcaption class=\"wp-element-caption\">Eczema can cause redness, blisters, and flaking. BruceBlaus via <a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Eczema.png\" target=\"_blank\" rel=\"noreferrer noopener\">Wikipedia<\/a>. CC-<a href=\"https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/deed.en\" target=\"_blank\" rel=\"noreferrer noopener\">Attribution-Share Alike 4.0 International<\/a><\/figcaption><\/figure>\n\n\n\n<p>The condition often occurs as flare-ups, in which the symptoms are present for a while and then go into remission, a time in which no symptoms are present. Some patients experience remission for up to several years.&nbsp;<\/p>\n\n\n\n<p>People with atopic eczema tend to have other allergic conditions such as <a href=\"https:\/\/nebula.org\/blog\/is-asthma-genetic\/\">asthma<\/a> and hay fever. They may also be at higher risk for skin infections (when repeated scratching breaks the skin), irritant hand dermatitis, and allergic contact dermatitis.<\/p>\n\n\n\n<p>There may also be an increased risk of other inflammatory disorders, including inflammatory bowel disease (<a href=\"https:\/\/nebula.org\/blog\/is-crohns-disease-genetic\/\">Crohn\u2019s disease<\/a> and <a href=\"https:\/\/nebula.org\/blog\/is-ulcerative-colitis-genetic\/\">ulcerative colitis<\/a>), <a href=\"https:\/\/nebula.org\/blog\/is-rheumatoid-arthritis-genetic\/\">rheumatoid arthritis<\/a>, and hair loss caused by a malfunctioning immune reaction (<a href=\"https:\/\/nebula.org\/blog\/is-alopecia-genetic\/\">alopecia areata<\/a>). In addition, children may experience behavioral complications such as <a href=\"https:\/\/nebula.org\/blog\/is-adhd-genetic\/\">ADHD<\/a> and <a href=\"https:\/\/nebula.org\/blog\/is-mental-illness-genetic\/\">depression<\/a>.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-causes\"><strong>Causes<\/strong><\/h2>\n\n\n\n<p>Although the cause of eczema is unknown, experts largely believe it is a combination of genetic and environmental factors (such as living with a pet). The condition results when immune cells are turned on in response to an outside allergen and causes inflammation in the skin.&nbsp;<\/p>\n\n\n\n<p>Some of the most common eczema triggers listed by the <a href=\"https:\/\/nationaleczema.org\/eczema\/causes-and-triggers-of-eczema\/\" target=\"_blank\" rel=\"noreferrer noopener\">National Eczema Association<\/a> include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Dry skin&nbsp;<\/li>\n\n\n\n<li>Irritants such as\n<ul class=\"wp-block-list\">\n<li>metals (especially nickel)<\/li>\n\n\n\n<li>cigarette smoke<\/li>\n\n\n\n<li>soaps and household cleansers<\/li>\n\n\n\n<li>fragrances<\/li>\n\n\n\n<li>certain fabrics like wool and polyester<\/li>\n\n\n\n<li>antibacterial ointments like neomycin and bacitracin<\/li>\n\n\n\n<li>formaldehyde (found in household disinfectants<\/li>\n\n\n\n<li>some vaccines<\/li>\n\n\n\n<li>glues and adhesives<\/li>\n\n\n\n<li>isothiazolinone, an antibacterial found in personal care products like shampoos<\/li>\n\n\n\n<li>Cocamidopropyl betaine (used to thicken shampoos and lotions)<\/li>\n\n\n\n<li>paraphenylenediamine (used in leather dyes and temporary tattoos, among others)<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li>Stress<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img decoding=\"async\" width=\"468\" height=\"468\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2023\/03\/Atopic_eczema_-_common_irritants.jpg\" alt=\"Eczema triggers\" class=\"wp-image-39116\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2023\/03\/Atopic_eczema_-_common_irritants.jpg 468w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2023\/03\/Atopic_eczema_-_common_irritants-300x300.jpg 300w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2023\/03\/Atopic_eczema_-_common_irritants-150x150.jpg 150w\" sizes=\"(max-width: 468px) 100vw, 468px\" \/><figcaption class=\"wp-element-caption\">Common triggers that can lead to a flare up. <br>Dyron via <a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Atopic_eczema_-_common_irritants.jpg\" target=\"_blank\" rel=\"noreferrer noopener\">Wikipedia<\/a>. CC-<a href=\"https:\/\/creativecommons.org\/licenses\/by-sa\/3.0\/deed.en\" target=\"_blank\" rel=\"noreferrer noopener\">Attribution-Share Alike 3.0 Unported<\/a><\/figcaption><\/figure>\n\n\n\n<p>The greatest risk factor in developing eczema is having a family history of the disorder or a history of allergies (including food allergies), hay fever, or asthma.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-diagnosis\"><strong>Diagnosis<\/strong><\/h2>\n\n\n\n<p>A specialist who observes your skin and symptoms often diagnoses the condition. The doctor will look for the classic signs of redness and dryness. Usually, this is enough for a diagnosis. However, your doctor may order other tests if they need to rule out other conditions or have other concerns.&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>An allergy skin test<\/li>\n\n\n\n<li>Blood tests to check for causes of the rash that might be unrelated to dermatitis<\/li>\n\n\n\n<li>A skin biopsy to distinguish one type of dermatitis from another<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-treatment\"><strong>Treatment<\/strong><\/h2>\n\n\n\n<p>Does eczema go away eventually? As mentioned earlier, this chronic skin disease has no cure, but patients can keep it under control. Options for treating eczema are available, although their effectiveness varies between patients. How long does eczema last will depend on consistent treatment and the patient\u2019s particular response.&nbsp;<\/p>\n\n\n\n<p>Some changes to your daily routine and skin care may significantly improve your symptoms. Many of them focus on moisturizing your skin.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Using a humidifier in dry environments<\/li>\n\n\n\n<li>Creams and ointments that seal in moisture such as petroleum jelly<\/li>\n\n\n\n<li>Using mild soaps, detergents, and other products that are free of perfumes, dyes, and alcohol. These products are usually labeled as \u201cfragrance-free,\u201d \u201chypoallergenic,\u201d or \u201cfor sensitive skin.\u201d&nbsp;<\/li>\n\n\n\n<li>Using skin products that contain ceramide<\/li>\n\n\n\n<li>Taking over the counter cortisone creams and ointments and\/or antihistamines<\/li>\n\n\n\n<li>Taking special baths such as oatmeal, salt water, vinegar, and bleach baths<\/li>\n\n\n\n<li>After bathing, gently pat the skin dry instead of rubbing<\/li>\n<\/ul>\n\n\n\n<p>If moisturizing and over the counter skin care products are not enough, a health care professional may recommend the following options summarized on Mayo Clinic:<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-medications\">Medications<\/h3>\n\n\n\n<p><strong>Prescription creams:<\/strong> These are usually a prescription corticosteroid cream or ointment. It\u2019s important to follow the instructions as overuse may cause side effects, including stretch marks that may become permanent.<\/p>\n\n\n\n<p>Other creams may contain drugs called calcineurin inhibitors that affect your immune system. People older than age 2 can use these products to help control the skin reaction. You should avoid strong sunlight when using these products.<\/p>\n\n\n\n<p><strong>Antibiotics:<\/strong> Your doctor may prescribe an antibiotic cream if your skin has a bacterial infection or if there are open sores or cracks from scratching.<\/p>\n\n\n\n<p><strong>Oral corticosteroids:<\/strong> These drugs are effective but can&#8217;t be used long term because of potentially serious side effects. They usually are only prescribed in the most severe cases.&nbsp;<\/p>\n\n\n\n<p><strong>Biologics:<\/strong> The Food and Drug Administration (FDA) has recently approved a new, injectable drug for the condition called dupilumab (Dupixent). It is used for severe cases that do not respond well to other treatment options. Studies have shown it to be safe if used as directed. It is very expensive.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-light-therapy\">Light therapy<\/h3>\n\n\n\n<p>If medications are not effective, your doctor may recommend a type of light therapy that exposes the skin to different kinds of light. One option is phototherapy, in which the skin is exposed to controlled amounts of natural sunlight. Other forms include artificial ultraviolet A (UVA) and narrow-band ultraviolet B (UVB). These treatments can be used alone or in combination with medication.<\/p>\n\n\n\n<p>Side effects of this treatment include accelerated skin aging and an increased risk of skin cancer, so it is important to speak with your doctor regarding this therapy. Because of these risks, it is rarely recommended for children and never provided for infants.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-infants-and-young-children\">Infants and young children<\/h3>\n\n\n\n<p>For infants, the treatment options are more limited and may include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Identifying and avoiding skin irritants, including in clothing and laundry detergent<\/li>\n\n\n\n<li>Avoiding extreme temperatures<\/li>\n\n\n\n<li>Skin lubrication with bath oils, ointments, or creams<\/li>\n<\/ul>\n\n\n\n<p>If the condition does not improve, some pediatricians may prescribe prescription-strength medication to help.<\/p>\n\n\n\n<p>If you liked this article, you should check out our other posts in the <a href=\"https:\/\/nebula.org\/blog\/nebula-library-unlocking-genetic-research\/\">Nebula Research Library<\/a>, including those that cover <a href=\"https:\/\/nebula.org\/blog\/is-psoriasis-genetic\/\">psoriasis<\/a> and <a href=\"https:\/\/nebula.org\/blog\/is-acne-genetic\/\">acne<\/a>. You may also be interested in the National Institutes of Health&#8217;s website.<\/p>\n\n\n\n<p class=\"has-medium-font-size\">March 31, 2023<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nebula Genomics DNA Report for Eczema Is eczema genetic? We created a DNA report based on a study that attempted to answer this question. Below you can see a SAMPLE DNA report. To get your personalized DNA report, purchase our &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"ast-button\" href=\"https:\/\/nebula.org\/blog\/is-eczema-genetic\/\"> <span class=\"screen-reader-text\">Atopic dermatitis &#8211; Is Eczema Genetic?<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":1844,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[50],"tags":[],"class_list":["post-1843","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.13 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Is Eczema Genetic? | Decode your DNA and learn about your risks!<\/title>\n<meta name=\"description\" content=\"Is eczema genetic? Upload your DNA data, explore genetic variants linked to atopic dermatitis and discover your polygenic score.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nebula.org\/blog\/is-eczema-genetic\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Is Eczema Genetic? | Decode your DNA and learn about your risks!\" \/>\n<meta property=\"og:description\" content=\"Is eczema genetic? Upload your DNA data, explore genetic variants linked to atopic dermatitis and discover your polygenic score.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nebula.org\/blog\/is-eczema-genetic\/\" \/>\n<meta property=\"og:site_name\" content=\"Nebula Genomics Blog\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/facebook.com\/nebulagenomics\" \/>\n<meta property=\"article:published_time\" content=\"2023-03-21T08:53:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-05-07T20:07:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/04\/person-pouring-plastic-tube-bottle-1029896-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"924\" \/>\n\t<meta property=\"og:image:height\" content=\"617\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Garrett Dunlap, B.S.\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:site\" content=\"@nebulagenomics\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Garrett Dunlap, B.S.\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"10 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/nebula.org\/blog\/is-eczema-genetic\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/nebula.org\/blog\/is-eczema-genetic\/\"},\"author\":{\"name\":\"Garrett Dunlap, B.S.\",\"@id\":\"https:\/\/nebula.org\/blog\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e\"},\"headline\":\"Atopic dermatitis &#8211; Is Eczema Genetic?\",\"datePublished\":\"2023-03-21T08:53:00+00:00\",\"dateModified\":\"2024-05-07T20:07:07+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/nebula.org\/blog\/is-eczema-genetic\/\"},\"wordCount\":1974,\"publisher\":{\"@id\":\"https:\/\/nebula.org\/blog\/#organization\"},\"articleSection\":[\"Reports\"],\"inLanguage\":\"en-US\",\"accessibilityFeature\":[\"tableOfContents\"]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/nebula.org\/blog\/is-eczema-genetic\/\",\"url\":\"https:\/\/nebula.org\/blog\/is-eczema-genetic\/\",\"name\":\"Is Eczema Genetic? | Decode your DNA and learn about your risks!\",\"isPartOf\":{\"@id\":\"https:\/\/nebula.org\/blog\/#website\"},\"datePublished\":\"2023-03-21T08:53:00+00:00\",\"dateModified\":\"2024-05-07T20:07:07+00:00\",\"description\":\"Is eczema genetic? Upload your DNA data, explore genetic variants linked to atopic dermatitis and discover your polygenic score.\",\"breadcrumb\":{\"@id\":\"https:\/\/nebula.org\/blog\/is-eczema-genetic\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/nebula.org\/blog\/is-eczema-genetic\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/nebula.org\/blog\/is-eczema-genetic\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/nebula.org\/blog\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Atopic dermatitis &#8211; Is Eczema Genetic?\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/nebula.org\/blog\/#website\",\"url\":\"https:\/\/nebula.org\/blog\/\",\"name\":\"Nebula Genomics Blog\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/nebula.org\/blog\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/nebula.org\/blog\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/nebula.org\/blog\/#organization\",\"name\":\"Nebula Genomics\",\"url\":\"https:\/\/nebula.org\/blog\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/nebula.org\/blog\/#\/schema\/logo\/image\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"Nebula Genomics\"},\"image\":{\"@id\":\"https:\/\/nebula.org\/blog\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/facebook.com\/nebulagenomics\",\"https:\/\/twitter.com\/nebulagenomics\",\"https:\/\/www.instagram.com\/nebulagenomics\/\",\"https:\/\/www.linkedin.com\/company\/nebula-genomics\/\",\"https:\/\/en.wikipedia.org\/wiki\/Nebula_Genomics\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/nebula.org\/blog\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e\",\"name\":\"Garrett Dunlap, B.S.\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/nebula.org\/blog\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g\",\"caption\":\"Garrett Dunlap, B.S.\"},\"description\":\"Garrett Dunlap earned a B.S. in Biology from Case Western Reserve University with a minor in Political Science. He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University.\u00a0He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.\",\"sameAs\":[\"https:\/\/nebula.org\/whole-genome-sequencing\/\"],\"url\":\"https:\/\/nebula.org\/blog\/author\/garrett-dunlap\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Is Eczema Genetic? | Decode your DNA and learn about your risks!","description":"Is eczema genetic? Upload your DNA data, explore genetic variants linked to atopic dermatitis and discover your polygenic score.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/nebula.org\/blog\/is-eczema-genetic\/","og_locale":"en_US","og_type":"article","og_title":"Is Eczema Genetic? | Decode your DNA and learn about your risks!","og_description":"Is eczema genetic? Upload your DNA data, explore genetic variants linked to atopic dermatitis and discover your polygenic score.","og_url":"https:\/\/nebula.org\/blog\/is-eczema-genetic\/","og_site_name":"Nebula Genomics Blog","article_publisher":"https:\/\/facebook.com\/nebulagenomics","article_published_time":"2023-03-21T08:53:00+00:00","article_modified_time":"2024-05-07T20:07:07+00:00","og_image":[{"width":924,"height":617,"url":"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2020\/04\/person-pouring-plastic-tube-bottle-1029896-scaled.jpg","type":"image\/jpeg"}],"author":"Garrett Dunlap, B.S.","twitter_card":"summary_large_image","twitter_creator":"@nebulagenomics","twitter_site":"@nebulagenomics","twitter_misc":{"Written by":"Garrett Dunlap, B.S.","Est. reading time":"10 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/nebula.org\/blog\/is-eczema-genetic\/#article","isPartOf":{"@id":"https:\/\/nebula.org\/blog\/is-eczema-genetic\/"},"author":{"name":"Garrett Dunlap, B.S.","@id":"https:\/\/nebula.org\/blog\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e"},"headline":"Atopic dermatitis &#8211; Is Eczema Genetic?","datePublished":"2023-03-21T08:53:00+00:00","dateModified":"2024-05-07T20:07:07+00:00","mainEntityOfPage":{"@id":"https:\/\/nebula.org\/blog\/is-eczema-genetic\/"},"wordCount":1974,"publisher":{"@id":"https:\/\/nebula.org\/blog\/#organization"},"articleSection":["Reports"],"inLanguage":"en-US","accessibilityFeature":["tableOfContents"]},{"@type":"WebPage","@id":"https:\/\/nebula.org\/blog\/is-eczema-genetic\/","url":"https:\/\/nebula.org\/blog\/is-eczema-genetic\/","name":"Is Eczema Genetic? | Decode your DNA and learn about your risks!","isPartOf":{"@id":"https:\/\/nebula.org\/blog\/#website"},"datePublished":"2023-03-21T08:53:00+00:00","dateModified":"2024-05-07T20:07:07+00:00","description":"Is eczema genetic? Upload your DNA data, explore genetic variants linked to atopic dermatitis and discover your polygenic score.","breadcrumb":{"@id":"https:\/\/nebula.org\/blog\/is-eczema-genetic\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/nebula.org\/blog\/is-eczema-genetic\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/nebula.org\/blog\/is-eczema-genetic\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/nebula.org\/blog\/"},{"@type":"ListItem","position":2,"name":"Atopic dermatitis &#8211; Is Eczema Genetic?"}]},{"@type":"WebSite","@id":"https:\/\/nebula.org\/blog\/#website","url":"https:\/\/nebula.org\/blog\/","name":"Nebula Genomics Blog","description":"","publisher":{"@id":"https:\/\/nebula.org\/blog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/nebula.org\/blog\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/nebula.org\/blog\/#organization","name":"Nebula Genomics","url":"https:\/\/nebula.org\/blog\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/nebula.org\/blog\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"Nebula Genomics"},"image":{"@id":"https:\/\/nebula.org\/blog\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/facebook.com\/nebulagenomics","https:\/\/twitter.com\/nebulagenomics","https:\/\/www.instagram.com\/nebulagenomics\/","https:\/\/www.linkedin.com\/company\/nebula-genomics\/","https:\/\/en.wikipedia.org\/wiki\/Nebula_Genomics"]},{"@type":"Person","@id":"https:\/\/nebula.org\/blog\/#\/schema\/person\/b7bd0a490f115d1d931c33eed922af4e","name":"Garrett Dunlap, B.S.","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/nebula.org\/blog\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/32fb6e0dbc7e0bac908b0f23ea6ed5ec?s=96&d=mm&r=g","caption":"Garrett Dunlap, B.S."},"description":"Garrett Dunlap earned a B.S. in Biology from Case Western Reserve University with a minor in Political Science. He earned an M.S. and is currently a Ph.D. Candidate in the Biological and Biomedical Sciences (BBS) Ph.D. program at Harvard University.\u00a0He has experience in science policy as an intern at the Science and Innovation Network where he assisted in the science diplomacy functions of the British Consulate-General and as a research associate at TScan Therapeutics. He is also interested in science communication and writing. You can read more about Garrett's experience and publications on LinkedIn and ORCID.","sameAs":["https:\/\/nebula.org\/whole-genome-sequencing\/"],"url":"https:\/\/nebula.org\/blog\/author\/garrett-dunlap\/"}]}},"_links":{"self":[{"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/posts\/1843","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/comments?post=1843"}],"version-history":[{"count":0,"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/posts\/1843\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/media\/1844"}],"wp:attachment":[{"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/media?parent=1843"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/categories?post=1843"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nebula.org\/blog\/wp-json\/wp\/v2\/tags?post=1843"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}