{"id":2499,"date":"2020-10-31T23:40:30","date_gmt":"2020-11-01T03:40:30","guid":{"rendered":"https:\/\/nebula.org\/blog\/?p=2499"},"modified":"2024-05-08T10:09:00","modified_gmt":"2024-05-08T14:09:00","slug":"cannabis-use-disorder-johnson-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/cannabis-use-disorder-johnson-2020\/","title":{"rendered":"Cannabis use disorder (Johnson, 2020)"},"content":{"rendered":"\n<p><strong>STUDY TITLE: <\/strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33096046\/\">A large-scale genome-wide association study meta-analysis of cannabis use disorder<\/a><\/p>\n\n\n\n<p><strong>SUMMARY:<\/strong> Identification of 2 genomic regions associated with cannabis use disorder.<\/p>\n\n\n\n<p><strong>OVERVIEW: <\/strong>In the United States, over 20 million people consume cannabis every month. About 1 in 10 users of cannabis will become dependent, leading to a condition known as cannabis use disorder. Individuals afflicted by <a href=\"https:\/\/pbinstitute.com\/marijuana\/\" target=\"_blank\" rel=\"noreferrer noopener\">cannabis use disorder<\/a> may develop irritability, memory problems, and depression. It is estimated that over 50% of an individual\u2019s risk of developing cannabis use disorder can be explained by genetic factors.&nbsp;This genome-wide association study found 2 regions of the genome associated with cannabis use disorder after examining genetic data of over 380,000 individuals of European and African ancestries. One of the discovered genetic variants is located in a gene known as FOXP2, which has previously been shown to play a role in speech and language development. The study also found a positive association between the risk of developing cannabis use disorder and the risk of developing <a href=\"https:\/\/nebula.org\/blog\/is-adhd-genetic\/\">ADHD<\/a>, schizophrenia, and depression.<\/p>\n\n\n\n<p><strong>DID YOU KNOW?<\/strong> Cannabis use can greatly affect coordination. Driving or use of other machinery under the influence of cannabis can be extremely dangerous. A 1990 study found that employees who tested positive for cannabis on a pre-employment drug test were prone to 55% more industrial accidents and 85% more injuries than their co-workers who tested negative. <a href=\"https:\/\/www.drugabuse.gov\/publications\/research-reports\/marijuana\/how-does-marijuana-use-affect-school-work-social-life\" target=\"_blank\" rel=\"noreferrer noopener\">[SOURCE]<\/a><\/p>\n\n\n\n<p><strong>SAMPLE RESULTS:<\/strong> Learn more about the<a href=\"https:\/\/nebula.org\/blog\/nebula-library-unlocking-genetic-research\/\"> Nebula Research Library<\/a>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"886\" height=\"512\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2024\/05\/Screenshot-2024-05-07-at-2.30.10\u202fPM.png\" alt=\"\" class=\"wp-image-45678\" style=\"object-fit:cover\" srcset=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2024\/05\/Screenshot-2024-05-07-at-2.30.10\u202fPM.png 886w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2024\/05\/Screenshot-2024-05-07-at-2.30.10\u202fPM-300x173.png 300w, https:\/\/nebula.org\/blog\/wp-content\/uploads\/2024\/05\/Screenshot-2024-05-07-at-2.30.10\u202fPM-768x444.png 768w\" sizes=\"(max-width: 886px) 100vw, 886px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>ADDITIONAL RESOURCES:<\/strong><br><a href=\"https:\/\/www.youtube.com\/watch?v=FsJzCdFlpyQ\" target=\"_blank\" rel=\"noreferrer noopener\">How weed works (Video)<\/a><br><a href=\"https:\/\/myhealth.alberta.ca\/health\/AfterCareInformation\/pages\/conditions.aspx?hwid=abr9729&amp;\" target=\"_blank\" rel=\"noreferrer noopener\">Cannabis use disorder<\/a><\/p>\n\n\n\n<p><strong>YOU MAY ALSO BE INTERESTED IN:<br><\/strong><a href=\"https:\/\/nebula.org\/blog\/genetics-of-cannabis-use-disorder-demontis-2019\/\">Cannabis Use Disorder (Demontis, 2019)<\/a><br><a href=\"https:\/\/nebula.org\/blog\/genetics-of-heavy-alcohol-consumption-thompson-2020\/\">Heavy Alcohol Consumption (Thompson, 2020)<\/a><br><a href=\"https:\/\/nebula.org\/blog\/genetics-of-alcohol-consumption-evangelou-2019\/\">Alcohol Consumption (Evangelou, 2019)<\/a><\/p>\n\n\n\n<p><strong>WEEKLY UPDATE:<\/strong> November 1, 2020<\/p>\n","protected":false},"excerpt":{"rendered":"<p>STUDY TITLE: A large-scale genome-wide association study meta-analysis of cannabis use disorder SUMMARY: Identification of 2 genomic regions associated with cannabis use disorder. OVERVIEW: In the United States, over 20 million people consume cannabis every month. About 1 in 10 &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"ast-button\" href=\"https:\/\/nebula.org\/blog\/cannabis-use-disorder-johnson-2020\/\"> <span class=\"screen-reader-text\">Cannabis use disorder (Johnson, 2020)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":2500,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[50],"tags":[],"class_list":["post-2499","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports"],"yoast_head":"<!-- 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