{"id":2501,"date":"2020-10-31T23:46:43","date_gmt":"2020-11-01T03:46:43","guid":{"rendered":"https:\/\/nebula.org\/blog\/?p=2501"},"modified":"2024-05-07T15:04:00","modified_gmt":"2024-05-07T19:04:00","slug":"sleep-quality-khoury-2020","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/sleep-quality-khoury-2020\/","title":{"rendered":"Sleep quality (Khoury, 2020)"},"content":{"rendered":"\n<p><strong>STUDY TITLE: <\/strong><a href=\"https:\/\/academic.oup.com\/sleep\/advance-article-abstract\/doi\/10.1093\/sleep\/zsaa211\/5920163?redirectedFrom=fulltext\">Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons<\/a><\/p>\n\n\n\n<p><strong>SUMMARY:<\/strong> Identification of 3 regions of the genome associated with sleep quality.<\/p>\n\n\n\n<p><strong>OVERVIEW: <\/strong>Sleep quality is very important for a person\u2019s overall health and well-being. Poor sleep has been shown to lead to various health issues, ranging from heart disease to depression. Sleep quality is determined by multiple factors including sleep duration, the time it takes to fall asleep, and the number of times a person wakes up during the night. It\u2019s estimated that genetic factors may explain over 30% of the observed variation in quality of sleep. To identify those genetic factors, this genome-wide association study examined over 100,000 individuals across different ethnicities.&nbsp;The study discovered 3 regions of the genome associated with sleep quality. One of the implicated genes, ATOH8, is known to play a role in the development of the brain, kidneys, and other organs. Another variant is located between two genes: NPY and MPP6. Both these genes are known to be active in the brain, and NPY in particular has been previously found to help regulate the sleep process.<\/p>\n\n\n\n<p><strong>DID YOU KNOW?<\/strong> Regular exercise, perhaps as little as 10-30 minutes per day, can help boost sleep quality. Furthermore, exercising in the morning or afternoon may be more beneficial for sleep quality than working out later in the evening. <a href=\"https:\/\/www.sleepfoundation.org\/articles\/how-exercise-impacts-sleep-quality\" target=\"_blank\" rel=\"noreferrer noopener\">[SOURCE]<\/a><\/p>\n\n\n\n<p><strong>SAMPLE RESULTS:<\/strong> Learn more about the<a href=\"https:\/\/nebula.org\/blog\/nebula-library-unlocking-genetic-research\/\"> Nebula Research Library<\/a>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" src=\"https:\/\/nebula.org\/blog\/wp-content\/uploads\/2024\/05\/Screenshot-2024-05-07-at-2.30.10\u202fPM.png\" alt=\"\" class=\"wp-image-45678\" style=\"width:752px;height:275px\" width=\"752\" height=\"275\"\/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>ADDITIONAL RESOURCES:<\/strong><br><a href=\"https:\/\/www.youtube.com\/watch?v=aLNhfVCa5qY\" target=\"_blank\" rel=\"noreferrer noopener\">The science of sleep (Video)<\/a><br><a href=\"https:\/\/www.cancer.org\/latest-news\/how-to-get-more-sleep.html\" target=\"_blank\" rel=\"noreferrer noopener\">10 tips to get more sleep<\/a><\/p>\n\n\n\n<p><strong>YOU MAY ALSO BE INTERESTED IN:<br><\/strong><a href=\"https:\/\/nebula.org\/blog\/genetics-of-daytime-sleepiness-wang-2019\/\">Daytime sleepiness (Wang, 2019)<\/a><br><a href=\"https:\/\/nebula.org\/blog\/genetics-of-snoring-manousaki-2020\/\">Snoring (Campos, 2020)<\/a><br><a href=\"https:\/\/nebula.org\/blog\/genetics-of-well-being-baselmans-2019\/\">Well-being (Baselmans, 2019)<\/a><\/p>\n\n\n\n<p><strong>WEEKLY UPDATE:<\/strong> November 1, 2020<\/p>\n","protected":false},"excerpt":{"rendered":"<p>STUDY TITLE: Multi-ethnic GWAS and meta-analysis of sleep quality identify MPP6 as a novel gene that functions in sleep center neurons SUMMARY: Identification of 3 regions of the genome associated with sleep quality. OVERVIEW: Sleep quality is very important for &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"ast-button\" href=\"https:\/\/nebula.org\/blog\/sleep-quality-khoury-2020\/\"> <span class=\"screen-reader-text\">Sleep quality (Khoury, 2020)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":2502,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[50],"tags":[],"class_list":["post-2501","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports"],"yoast_head":"<!-- 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