{"id":959,"date":"2020-04-09T23:23:00","date_gmt":"2020-04-10T03:23:00","guid":{"rendered":"https:\/\/nebula.org\/blog\/?p=959"},"modified":"2022-10-11T08:43:52","modified_gmt":"2022-10-11T12:43:52","slug":"genetics-of-keratoconus-mccomish-2019","status":"publish","type":"post","link":"https:\/\/nebula.org\/blog\/genetics-of-keratoconus-mccomish-2019\/","title":{"rendered":"Thinning Cornea: Keratoconus (McComish, 2019)"},"content":{"rendered":"\n

STUDY TITLE: <\/strong>Association of Genetic Variation With Keratoconus <\/a><\/p>\n\n\n\n

SUMMARY:<\/strong> Discovery of 3 genetic regions associated with keratoconus, an eye condition characterized by thinning of the cornea.<\/p>\n\n\n\n

OVERVIEW:<\/strong> The cornea is a thin, clear layer of tissue that covers the front of the eye. Like a car\u2019s windshield, the cornea enables you to see clearly while protecting the inner parts of the eye. Keratoconus is a disease characterized by thinning and deformation of the cornea which can lead to blurry vision and nearsightedness. This genome-wide association study sought to discover variants associated with an increased risk of developing keratoconus. By examining the genetic information of nearly 6,000 individuals, researchers identified 3 genetic regions associated with the condition.<\/p>\n\n\n\n

DID YOU KNOW?<\/strong> Long term use of contact lenses can lead to a reduced thickness of the cornea. Limiting the use of contact lenses to a maximum of 14-16 hours per day can help reduce this and other harmful effects. [SOURCE]<\/a><\/p>\n\n\n\n

SAMPLE RESULTS:<\/strong> Learn more about the Nebula Research Library<\/a>. <\/p>\n\n\n\n

\"keratoconus<\/a><\/figure>\n\n\n\n

<\/p>\n\n\n\n

KERATOCONUS-ASSOCIATED VARIANTS:<\/strong> rs138378, rs61876744, rs10831500<\/p>\n\n\n\n

ADDITIONAL RESOURCES:<\/strong>
Keratoconus<\/a><\/p>\n\n\n\n

WEEKLY UPDATE:<\/strong> January 3, 2020<\/p>\n","protected":false},"excerpt":{"rendered":"

STUDY TITLE: Association of Genetic Variation With Keratoconus  SUMMARY: Discovery of 3 genetic regions associated with keratoconus, an eye condition characterized by thinning of the cornea. OVERVIEW: The cornea is a thin, clear layer of tissue that covers the front …<\/p>\n

Thinning Cornea: Keratoconus (McComish, 2019)<\/span> Read More \u00bb<\/a><\/p>\n","protected":false},"author":12,"featured_media":1062,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","_FSMCFIC_featured_image_caption":"","_FSMCFIC_featured_image_nocaption":"","_FSMCFIC_featured_image_hide":"","footnotes":""},"categories":[50],"tags":[],"class_list":["post-959","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reports"],"yoast_head":"\nThe 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