RESUMEN: Identificación de 440 variantes genéticas asociadas con la triglicéridos nivel en sangre y análisis de su contribución al riesgo de enfermedad coronaria.
DESCRIPCIÓN: La enfermedad cardíaca coronaria (CHD) es una afección que se desarrolla cuando las arterias del corazón no pueden suministrar suficiente oxígeno al músculo cardíaco. La enfermedad coronaria es la principal causa de muerte en los Estados Unidos. Ocurre cuando placa se acumula en las arterias del corazón y bloquea el flujo sanguíneo al corazón. Arterial placa Consta de múltiples sustancias que circulan en la sangre. Una de las sustancias que examinó el estudio es triglicéridos . Con este fin, este estudio analizó datos genéticos de más de 440.000 individuos de ascendencia europea para identificar regiones genómicas asociadas con triglicéridos niveles en la sangre. Los investigadores identificaron 440 variantes asociadas con triglicéridos 339 de los cuales se han descubierto recientemente. El trabajo posterior mostró que alta triglicéridos los niveles están asociados con un mayor riesgo de enfermedad coronaria. Sin embargo, esta asociación se debilitó ligeramente cuando los investigadores consideraron todas las grasas y proteínas en el estudio. Los resultados aún sugieren que triglicéridos juegan un papel importante en el desarrollo de enfermedades cardíacas.
¿SABÍAS? Los niveles altos de triglicéridos pueden aumentar su riesgo de padecer afecciones como ataque cardíaco y accidente cerebrovascular. También se han relacionado con enfermedades del páncreas y el hígado. Los médicos recomiendan hacer más ejercicio, perder peso y modificar su dieta para reducir los niveles de triglicéridos. [SOURCE]
RESULTADOS DE LA MUESTRA: Más información sobre el Biblioteca de investigación de nebulosa .
VARIANTES ASOCIADAS AL NIVEL DE TRIGLICERIDOS: rs7694869, rs6805924, rs56321085, rs973709, rs2054067, rs4002684, rs2110690, rs143076454, rs7826246, rs62130120, rs62064941, rs72917533, rs61975915, rs2070341, rs6924805, rs7186635, rs2774430, rs2131311, rs6913325, rs61780049, rs6722159, rs6000553, rs144738419, rs3017106, rs134551, rs6572807, rs62473520, rs2416759, rs9553567, rs4858894, rs1152847, rs2420477, rs11980456, rs4947121, rs1556124, rs11657201, rs76957426, rs34893217, rs293561, rs7077812, rs2187114, rs112162280, rs878409, rs7199293, rs394872, rs28624578, rs7136223, rs3758413, rs2705616, rs2017500, rs184694823, rs10863828, rs499293, rs498475, rs880315, rs7681288, rs76172517, rs10172544, rs80078546, rs117291242, rs78297458, rs77824033, rs71538127, rs55646464, rs2194411, rs75268115, rs4559942, rs2342371, rs12669911, rs4564007, rs320369, rs1728407, rs1281978, rs1133400, rs113266765, rs55837381, rs325485, rs2499797, rs7714361, rs10180284, rs74897213, rs9584870, rs7596814, rs10962680, rs7855395, rs9831084, rs7400002, rs10811662, rs7 424.120, rs4382584, rs7244, rs9496567, rs4128205, rs4714001, rs1340819, rs3784310, rs36061954, rs139453187, rs200293726, rs1835346, rs72691637, rs775633, rs2240533, rs144984216, rs11746801, rs73025562, rs9944241, rs3808477, rs2455821, rs11664106, rs6700266, rs56902258, rs4662414, rs2517887, rs1561928, rs12504746, rs933574, rs78588343, rs3826043, rs138191773, rs1347188, rs79357714, rs139386986, rs704, rs13101828, rs12454712, rs12422600, rs112403212, rs1149470, rs6506033, rs4909945, rs4802113, rs7631606, rs62427982, rs245051, rs12530679, rs111914893, rs9788220, rs9376511, rs79983121, rs8102873, rs852388, rs71473777, rs10792091, rs806973, rs193735, rs9600143, rs383091, rs34245505, rs7191623, rs62397245, rs57074291, rs61993685, rs146706984, rs77756595, rs11903847, rs11187027, rs55737395, rs149142833, rs1292065, rs6465120, rs573377651, rs6798755, rs10899490, rs9812100, rs200841050, rs10842703, rs6708784, rs58839393, rs8066985, rs35764600, rs12591786, rs9890200, rs62565259, rs2382825, rs12926 107, rs1126673, rs2131919, rs147011441, rs75398587, rs11722924, rs36043408, rs13066793, rs6517522, rs35763453, rs151235402, rs9943778, rs77631110, rs113439801, rs79311290, rs6068280, rs4709746, rs296360, rs62118471, rs1351394, rs10152471, rs11240358, rs140288, rs112424890, rs75225803, rs11078696, rs6424109, rs35859536, rs1171617, rs6093446, rs3829126, rs12472667, rs954244, rs9610329, rs9832727, rs6690181, rs9970140, rs77244849, rs41292412, rs11100083, rs9480889, rs581080, rs80276949, rs595767, rs34580448, rs2860183, rs867939, rs75679663, rs2237029, rs935168, rs78025076, rs55767272, rs4450871, rs10797996, rs7439032, rs12138136, rs4761234, rs7704653, rs35104374, rs6792725, rs1567353, rs921971, rs7018436, rs72644085, rs1861435, rs149778057, rs2812208, rs12440800, rs7260465, rs58953077, rs79634051, rs37538, rs490972, rs4675812, rs12600110, rs1365297, rs58324296, rs11030107, rs1316753, rs61885960, rs2288004, rs3731696, rs114052230, rs140874911, rs60610697, rs41785, rs4134963, rs3814883, rs12415159, rs61729990, rs11078597, rs2652806, rs7749305, rs4776793, rs4239538, rs6968865, rs62459095, rs213494, rs73221948, rs3822072, rs28577186, rs17326656, rs8025505, rs138751626, rs3820897, rs12880341, rs11228377, rs2071887, rs2277083, rs2278426, rs10242866, rs9561643, rs72904737, rs3131337, rs7274718, rs13107325, rs2035816, rs10797119, rs7239575, rs591939, rs5402, rs1938566, rs1064939, rs55966194, rs10243434, rs729761, rs116878033, rs2850245, rs11231161, rs10176110, rs9375694, rs563296, rs7138037, rs13101719, rs8126001, rs142385484, rs140107293, rs2773469, rs2487294, rs2519093, rs79287178, rs12610709, rs78376313, rs535241194, rs7735249, rs61830291, rs7134375, rs6458869, rs3103310, rs41273040, rs12185242, rs4976033, rs4969179, rs10775406, rs9274390, rs185139895, rs1800978, rs79192570, rs696825 , Rs72801474, rs10750766, rs1799831, rs580063, rs9817452, rs11781692, rs71603401, rs150555490, rs10422861, rs6486122, rs1009360, rs62084237, rs2917677, rs6531216, rs1045241, rs12749691, rs1030472, rs13269725, rs11118310, rs2523719, rs7215055, rs3890483, rs62271373, rs62117489, rs2699805 , rs67981690, rs113344423, rs79153732, rs58895965, rs1883711, rs11206374, rs150564454, rs2267373, rs36104871, rs3794695, rs73243877, rs192955957, rs41552812, rs76895963, rs1801689, rs11635675, rs28364531, rs326222, rs6800707, rs182636083, rs77009508, rs4760254, rs838133, rs114165349, rs4930724 , rs684773, rs2980755, rs6982308, rs2081687, rs186696265, rs114443260, rs12928099, rs7140110, rs6916318, rs4722551, rs56271783, rs4500049, rs72555385, rs540973884, rs863750, rs188247550, rs2925979, rs13108218, rs1532085, rs9378248, rs12446515, rs1495741, rs2068888, rs78058190, rs10822163 , rs6882076, rs4731701, rs3775228, rs78484485, rs3936511, rs13389219, rs28383314, rs2943645, rs1077835, rs75609851, rs998584, rs607 3958, rs308, rs139974673, rs150423652, rs7000494, rs174566, rs11122450, rs72836561, rs58542926, rs676210, rs116843064, rs5112, rs483082, rs9436661, rs680695, rs44046823, rs436661
RECURSOS ADICIONALES:
Enfermedad coronaria (video)
Enfermedad coronaria
Triglicéridos
ACTUALIZACIÓN SEMANAL: 5 de abril de 2020
