Niveau de triglycérides (Richardson, 2020)

L'image du «tri» dans les triglycérides fait référence aux trois chaînes d'acides gras.

TITRE DE L’ÉTUDE: Évaluation de la relation entre les lipides lipoprotéiques circulants et les apolipoprotéines avec risque de maladie coronarienne: une analyse randomisée mendélienne multivariée

SOMMAIRE: Identification de 440 variantes génétiques associées à la triglycéride taux sanguin et analyse de sa contribution au risque de maladie coronarienne.

LA DESCRIPTION: La maladie coronarienne (CHD) est une maladie qui se développe lorsque les artères du cœur ne peuvent pas fournir suffisamment d’oxygène au muscle cardiaque. La maladie coronarienne est la principale cause de décès aux États-Unis. Cela se produit lorsque plaque s’accumule dans les artères du cœur et bloque le flux sanguin vers le cœur. Artériel plaque se compose de plusieurs substances qui circulent dans le sang. L’une des substances examinées par l’étude est triglycéride . À cette fin, cette étude a analysé les données génétiques de plus de 440000 individus d’origine européenne pour identifier les régions génomiques associées à triglycéride niveaux sanguins. Les chercheurs ont identifié 440 variantes associées à triglycérides , Dont 339 nouvellement découverts. D’autres travaux ont montré que triglycéride les niveaux sont associés à un risque accru de maladie coronarienne. Cependant, cette association s’est légèrement affaiblie lorsque les chercheurs ont pris en compte toutes les graisses et protéines dans l’étude. Les résultats suggèrent encore que triglycérides jouent un rôle important dans le développement des maladies cardiaques.

LE SAVIEZ-VOUS? Des niveaux élevés de triglycérides peuvent augmenter votre risque d’affections telles que crise cardiaque et accident vasculaire cérébral. Ils ont également été liés à des maladies du pancréas et du foie. Les médecins recommandent de faire plus d’exercice, de perdre du poids et de modifier votre alimentation pour réduire les taux de triglycérides. [SOURCE]

EXEMPLE DE RÉSULTATS: En savoir plus sur Bibliothèque de recherche sur la nébuleuse .

Exemple de résultats pour le niveau de triglycérides

VARIANTES ASSOCIES AU NIVEAU DE TRIGLYCERIDE: rs7694869, rs6805924, rs56321085, rs973709, rs2054067, rs4002684, rs2110690, rs143076454, rs7826246, rs62130120, rs62064941, rs72917533, rs61975915, rs2070341, rs6924805, rs7186635, rs2774430, rs2131311, rs6913325, rs61780049, rs6722159, rs6000553, rs144738419, rs3017106, rs134551, rs6572807, rs62473520, rs2416759, rs9553567, rs4858894, rs1152847, rs2420477, rs11980456, rs4947121, rs1556124, rs11657201, rs76957426, rs34893217, rs293561, rs7077812, rs2187114, rs112162280, rs878409, rs7199293, rs394872, rs28624578, rs7136223, rs3758413, rs2705616, rs2017500, rs184694823, rs10863828, rs499293, rs498475, rs880315, rs7681288, rs76172517, rs10172544, rs80078546, rs117291242, rs78297458, rs77824033, rs71538127, rs55646464, rs2194411, rs75268115, rs4559942, rs2342371, rs12669911, rs4564007, rs320369, rs1728407, rs1281978, rs1133400, rs113266765, rs55837381, rs325485, rs2499797, rs7714361, rs10180284, rs74897213, rs9584870, rs7596814, rs10962680, rs7855395, rs9831084, rs7400002, rs10811662, rs700002, rs10811662 424120, rs4382584, rs7244, rs9496567, rs4128205, rs4714001, rs1340819, rs3784310, rs36061954, rs139453187, rs200293726, rs1835346, rs72691637, rs775633, rs2240533, rs144984216, rs11746801, rs73025562, rs9944241, rs3808477, rs2455821, rs11664106, rs6700266, rs56902258, rs4662414, rs2517887, rs1561928, rs12504746, rs933574, rs78588343, rs3826043, rs138191773, rs1347188, rs79357714, rs139386986, rs704, rs13101828, rs12454712, rs12422600, rs112403212, rs1149470, rs6506033, rs4909945, rs4802113, rs7631606, rs62427982, rs245051, rs12530679, rs111914893, rs9788220, rs9376511, rs79983121, rs8102873, rs852388, rs71473777, rs10792091, rs806973, rs193735, rs9600143, rs383091, rs34245505, rs7191623, rs62397245, rs57074291, rs61993685, rs146706984, rs77756595, rs11903847, rs11187027, rs55737395, rs149142833, rs1292065, rs6465120, rs573377651, rs6798755, rs10899490, rs9812100, rs200841050, rs10842703, rs6708784, rs58839393, rs8066985, rs35764600, rs12591786, rs9890200, rs62565259, rs2382825, rs12926 107, rs1126673, rs2131919, rs147011441, rs75398587, rs11722924, rs36043408, rs13066793, rs6517522, rs35763453, rs151235402, rs9943778, rs77631110, rs113439801, rs79311290, rs6068280, rs4709746, rs296360, rs62118471, rs1351394, rs10152471, rs11240358, rs140288, rs112424890, rs75225803, rs11078696, rs6424109, rs35859536, rs1171617, rs6093446, rs3829126, rs12472667, rs954244, rs9610329, rs9832727, rs6690181, rs9970140, rs77244849, rs41292412, rs11100083, rs9480889, rs581080, rs80276949, rs595767, rs34580448, rs2860183, rs867939, rs75679663, rs2237029, rs935168, rs78025076, rs55767272, rs4450871, rs10797996, rs7439032, rs12138136, rs4761234, rs7704653, rs35104374, rs6792725, rs1567353, rs921971, rs7018436, rs72644085, rs1861435, rs149778057, rs2812208, rs12440800, rs7260465, rs58953077, rs79634051, rs37538, rs490972, rs4675812, rs12600110, rs1365297, rs58324296, rs11030107, rs1316753, rs61885960, rs2288004, rs3731696, rs114052230, rs140874911, rs60610697, rs41785, rs4134963, rs3814883, rs12415159, rs61729990, rs11078597, rs2652806, rs7749305, rs4776793, rs4239538, rs6968865, rs62459095, rs213494, rs73221948, rs3822072, rs28577186, rs17326656, rs8025505, rs138751626, rs3820897, rs12880341, rs11228377, rs2071887, rs2277083, rs2278426, rs10242866, rs9561643, rs72904737, rs3131337, rs7274718, rs13107325, rs2035816, rs10797119, rs7239575, rs591939, rs5402, rs1938566, rs1064939, rs55966194, rs10243434, rs729761, rs116878033, rs2850245, rs11231161, rs10176110, rs9375694, rs563296, rs7138037, rs13101719, rs8126001, rs142385484, rs140107293, rs2773469, rs2487294, rs2519093, rs79287178, rs12610709, rs78376313, rs535241194, rs7735249, rs61830291, rs7134375, rs6458869, rs3103310, rs41273040, rs12185242, rs4976033, rs4969179, rs10775406, rs9274390, rs185139895, rs1800978, rs79192570, rs696825 , Rs72801474, rs10750766, rs1799831, rs580063, rs9817452, rs11781692, rs71603401, rs150555490, rs10422861, rs6486122, rs1009360, rs62084237, rs2917677, rs6531216, rs1045241, rs12749691, rs1030472, rs13269725, rs11118310, rs2523719, rs7215055, rs3890483, rs62271373, rs62117489, rs2699805 , rs67981690, rs113344423, rs79153732, rs58895965, rs1883711, rs11206374, rs150564454, rs2267373, rs36104871, rs3794695, rs73243877, rs192955957, rs41552812, rs76895963, rs1801689, rs11635675, rs28364531, rs326222, rs6800707, rs182636083, rs77009508, rs4760254, rs838133, rs114165349, rs4930724 , rs684773, rs2980755, rs6982308, rs2081687, rs186696265, rs114443260, rs12928099, rs7140110, rs6916318, rs4722551, rs56271783, rs4500049, rs72555385, rs540973884, rs863750, rs188247550, rs2925979, rs13108218, rs1532085, rs9378248, rs12446515, rs1495741, rs2068888, rs78058190, rs10822163 , rs6882076, rs4731701, rs3775228, rs78484485, rs3936511, rs13389219, rs28383314, rs2943645, rs1077835, rs75609851, rs998584, rs607 3958, rs308, rs139974673, rs150423652, rs7000494, rs174566, rs11122450, rs72836561, rs58542926, rs676210, rs116843064, rs5112, rs483082, rs9436661, rs483082, rs9436661, rs483082, rs9436661, rs483082, rs9436661, rs34666, rs34666, rs34661, rs34666

RESSOURCES ADDITIONNELLES:
Maladie coronarienne (vidéo)
Maladie coronarienne
Triglycérides

MISE À JOUR HEBDOMADAIRE: 5 avril 2020