Nivel de colesterol HDL (Richardson, 2020)

Ilustración de corazón rosa

TÍTULO DEL ESTUDIO: Evaluación de la relación entre los lípidos de lipoproteínas circulantes y las apolipoproteínas con el riesgo de enfermedad coronaria: un análisis de aleatorización mendeliana multivariable

RESUMEN: Identificación de 534 variantes genéticas asociadas al HDL colesterol nivel en sangre y análisis de su contribución al riesgo de enfermedad coronaria.

DESCRIPCIÓN: La enfermedad cardíaca coronaria (CHD) es una afección que se desarrolla cuando las arterias del corazón no pueden suministrar suficiente oxígeno al músculo cardíaco. La enfermedad coronaria es la principal causa de muerte en los Estados Unidos. Ocurre cuando placa se acumula en las arterias del corazón y bloquea el flujo sanguíneo al corazón. Arterial placa Consta de múltiples sustancias que circulan en la sangre. Una de las sustancias que examinó el estudio es la HDL (lipoproteína de alta densidad) colesterol , también conocido como el “bueno” colesterol . Con este fin, este estudio analizó datos genéticos de más de 440.000 individuos de ascendencia europea para identificar regiones genómicas asociadas con HDL. colesterol niveles en la sangre. Los investigadores identificaron 534 variantes genéticas, incluidas 383 variantes nuevas, asociadas con HDL colesterol niveles. El análisis mostró que un HDL alto colesterol El nivel está asociado con un menor riesgo de enfermedad coronaria. Sin embargo, esta asociación se debilitó cuando los investigadores consideraron todas las grasas y proteínas en el estudio. Los resultados del estudio aún sugieren que HDL colesterol juega un papel importante en el desarrollo de enfermedades cardíacas.

¿SABÍAS? El colesterol HDL a menudo se denomina colesterol “bueno” porque ayuda a su cuerpo a eliminar otros tipos de colesterol del torrente sanguíneo. Algunas formas de aumentar los niveles de colesterol HDL incluyen el ejercicio y una dieta baja en grasas trans. [SOURCE]

RESULTADOS DE LA MUESTRA: Más información sobre el Biblioteca de investigación de nebulosa .

Resultados de muestra para el nivel de colesterol HDL

VARIANTES ASOCIADAS AL NIVEL DE COLESTEROL HDL: rs9989419, rs1800588, rs1601934, rs343, rs964184, rs77960347, rs8086351, rs79600951, rs2740488, rs72836561, rs2281718, rs116843064, rs429358, rs174566, rs9987289, rs80005209, rs6073958, rs1800961, rs676210, rs11789603, rs13107325, rs1052373, rs2943645, rs10162642, rs12976395, rs921919, rs141469619, rs55781197, rs3768321, rs308, rs571848809, rs367070, rs686030, rs2925979, rs4871603, rs998584, rs75609851, rs737338, rs1054852, rs2792751, rs6469605, rs2066714, rs113740515, rs545858676, rs78058190, rs145276599, rs35493868, rs4731701, rs4969141, rs7136506, rs11658786, rs150844304, rs12422125, rs12224170, rs140584594, rs11228871, rs13389219, rs11228212, rs3184504, rs17138358, rs61352607, rs2263329, rs7817574, rs2256609, rs559355, rs2642438, rs6902116, rs58473820, rs193084249, rs2498786, rs11239536, rs79153732, rs61805075, rs116978226, rs12740374, rs3936511, rs7308864, rs56271783, rs144311893, rs13235365, rs11045171, rs6765484, rs771481, rs75662196, rs9647335, rs112001035, rs11967891, rs427301 0, rs62102718, rs35137994, rs12411732, rs75152587, rs4239651, rs10513801, rs2298624, rs11664369, rs133015, rs72959041, rs10233430, rs2297402, rs6824451, rs61435086, rs72823020, rs12928099, rs1043897, rs1047964, rs3775228, rs11066320, rs2523978, rs17326656, rs2068888, rs77403571, rs632057, rs6542680, rs72647336, rs62271373, rs73243877, rs72926946, rs11645157, rs9817452, rs2159607, rs142288236, rs2307111, rs10955991, rs4871624, rs7750688, rs7757193, rs142493909, rs907866, rs4650994, rs7925100, rs532436, rs267738, rs17309930, rs3129797, rs235314, rs1047891, rs3803501, rs7170463, rs13379043, rs8081548, rs117687565, rs142965311, rs10750766, rs12485478, rs3736802, rs6499102, rs1534696, rs2963468, rs55935382, rs12510382, rs1468642, rs112771035, rs3129962, rs11605837, rs10774579, rs4686739, rs2435307, rs74419430, rs11880219, rs6934962, rs2247355, rs4930352, rs66763009, rs1132274, rs10774439, rs34138141, rs62492368, rs10786114, rs11640494, rs9622830, rs703966, rs2289863, rs74735576, rs3814883, rs557933, rs11658872, rs10846690, rs16928809, rs2804894, rs35777071, rs13097947, rs34675318, rs141062196, rs8014289, rs10504477, rs1168114, rs3763236, rs830620, rs3732356, rs2862954, rs12650112, rs1446585, rs11118320, rs9608972, rs12150914, rs11075985, rs9604045, rs1045241, rs13076933, rs2723065, rs9274346, rs11231138, rs2268840, rs59104589, rs4356188, rs13220570, rs77631377, rs595767, rs77605964, rs3749748, rs41292412, rs116006942, rs367677, rs143474489, rs6457807, rs2298632, rs9657541, rs117230571, rs13269725, rs4979372, rs62112763, rs577525, rs1055582, rs2314338, rs3747973, rs78025076, rs6123685, rs9646167, rs4760, rs28876383, rs2011614, rs1611719, rs10761737, rs7595075, rs7158166, rs4788446, rs138352401, rs247901, rs728719 rs2237035, rs968050, rs11057468, rs140201358, rs4800356, rs75817747, rs76428106, rs11170516, rs6924387, rs74456742, rs10252234, rs6664374, rs13147189, rs62486442, rs9347737, rs147525635, rs62338910, rs140064750, rs2071379, rs76602912, rs34555420, rs1225053, rs75572195, rs113710278, rs150237291, rs34940374, rs76213248, rs2964007, rs2520096, rs35706812, rs73221948, rs9469583, rs6590207, rs11601507, rs12803463, rs79634051, rs13263821, rs2705616, rs9980311, rs330042, rs11021232, rs11631178, rs12411959, rs1884589, rs113761591, rs12814794, rs2585398, rs374039502, rs72729582, rs2910949, rs67344323, rs2204886, rs74500135, rs11688682, rs16969990, rs11687520, rs1663626, rs13066793, rs62092069, rs13144151, rs838777, rs3733890, rs34695471, rs55652051, rs17740942, rs28712486, rs11254464, rs13042367, rs12045101, rs12975319, rs1771582, rs7583067, rs2781668, rs73457437, rs11878235, rs73082723, rs150300171, rs12516070, rs32578, rs62428831, rs72801474, rs12686780, rs4875043, rs10950390, rs61884030, rs22 98214, rs15052, rs68006638, rs9884482, rs13323506, rs183078, rs4654395, rs78595810, rs17041868, rs61926301, rs185073199, rs7036107, rs72654647, rs112192770, rs200540247, rs248653, rs1240820, rs56105022, rs1086056, rs4078216, rs55801554, rs9877304, rs11043221, rs17566828, rs2417125, rs11883967, rs4947121, rs738409, rs10896581, rs183906992, rs2965169, rs11961755, rs62565259, rs2098918, rs77234291, rs1252425, rs77916918, rs7488780, rs72805692, rs2551980, rs4976033, rs61919816, rs6021914, rs73179655, rs113261881, rs28510484, rs74328314, rs12998038, rs57074291, rs10916239, rs1970811, rs75032664, rs7725218, rs6790951, rs8126001, rs13041173, rs3794752, rs1818917, rs11878604, rs1431659, rs72755439, rs13111599, rs2364723, rs7622114, rs7658082, rs9646934, rs254559, rs12921195, rs1412234, rs34717889, rs61596977, rs1083470, rs11171710, rs73151974, rs76530346, rs58298943, rs9526023, rs17124112, rs115912456, rs7251640, rs10438354, rs3825669, rs16975758, rs6940493, rs34720381, rs1894544, rs549058, rs 8127283, rs75246752, rs34830321, rs1349852, rs10826337, rs7903537, rs1155347, rs117499775, rs2100692, rs4691379, rs11938781, rs1862205, rs141440048, rs2339234, rs57348955, rs6806529, rs12926854, rs567056, rs76246107, rs4855582, rs56017932, rs2245477, rs2645979, rs79311290, rs11653260, rs2534596, rs6874833, rs6131012, rs7650845, rs6059958, rs3859588, rs6987377, rs75479205, rs11009262, rs1395221, rs201441, rs6738438, rs7316878, rs12146566, rs13300004, rs2362541, rs35580606, rs6762415, rs7826177, rs12692596, rs42125, rs6002946, rs680321, rs2750411, rs38166, rs4755720, rs8102873, rs10879184, rs11000468, rs11948445, rs139828053, rs2456722, rs35828909, rs36092527, rs10901802, rs34559316, rs61905599, rs7039168, rs1411432, rs7218647, rs9610329, rs16885512, rs2175766, rs13195251, rs28455602, rs3746915, rs4410790, rs56131490, rs61748951, rs12713007, rs4550673, rs514924, rs79616633, rs4997370, rs1955512, rs4924471, rs12705595, rs6893139, rs144567740, rs2414178, rs11202156, rs1517500, rs17185038, rs2302367, rs11546878, rs1012306, rs2663924, rs3903399, rs61993685, rs117435644, rs7188071, rs2155220, rs12119128, rs11622947, rs502627, rs78456138, rs546436456, rs73455693, rs12986742, rs67934334, rs454968, rs1760940, rs59737437, rs880674, rs1567353, rs445841, rs550916783, rs138026745, rs4233367, rs407133, rs254024, rs118128493

RECURSOS ADICIONALES:
Enfermedad coronaria (video)
Enfermedad coronaria
Colesterol LDL y HDL: Colesterol “malo” y “bueno”

ACTUALIZACIÓN SEMANAL: 5 de abril de 2020