Altura (Wood, 2014)

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TÍTULO DEL ESTUDIO: Definición del papel de la variación común en la arquitectura genómica y biológica de la estatura humana adulta

TÍTULO DEL ESTUDIO: Identificación de todo el genoma de 687 variantes asociadas con la altura.

VISIÓN GENERAL: En los últimos 150 años, la altura promedio de un ser humano ha aumentado alrededor de 4 pulgadas. Si bien los factores ambientales como la nutrición tienen una fuerte influencia en el crecimiento del cuerpo humano, está claro que la altura es un rasgo altamente heredable. De hecho, se cree que hasta el 80% de la altura de una persona está determinada genéticamente. Sin embargo, la altura es un rasgo muy complejo influenciado por muchas variantes en el genoma. Para identificar variantes genéticas asociadas a la altura, este estudio examinó a más de 250.000 individuos de ascendencia europea. Los investigadores descubrieron 697 variantes genéticas asociadas con la altura. En conjunto, estas variantes explican ~ 16% de las diferencias de altura observadas entre las personas. Algunas de las variantes identificadas son genes cercanos que están involucrados en el desarrollo de huesos y cartílagos.

¿SABÍAS? A partir de los 40 años, muchas personas comienzan a perder altura. Esto puede deberse a múltiples factores, como la compresión espinal relacionada con la edad y trastornos como la osteoporosis. El ejercicio y la nutrición saludable (que incluya mucho calcio) pueden ayudar a mantener huesos y músculos fuertes y limitar la pérdida de estatura. [FUENTE ]

RESULTADOS DE LA MUESTRA: Más información sobre el Biblioteca de investigación de nebulosa .

resultados de la muestra de altura humana

VARIANTES ANALIZADAS: rs724016, rs7692995, rs3791679, rs8756, rs143384, rs798497, rs3760318, rs806794, rs4896582, rs720390, rs4369779, rs3814333, rs3825199, rs12214804, rs552707, rs2079795, rs1155939, rs9292468, rs10859567, rs9392918, rs17556750, rs314263, rs1074683, rs4733724, rs7701414, rs3811958, rs2284746, rs42039, rs1036821, rs9428104, rs7870753, rs7652177, rs2093210, rs12538407, rs5742915, rs9650315, rs2289195, rs3118905, rs1884897, rs9967417, rs991967, rs3800461, rs2871865, rs4986172, rs1367226, rs11049611, rs1812175, rs4548838, rs4735677, rs1535466, rs16942341, rs7033487, rs10748128, rs10958476, rs7849585, rs4448343, rs2854207, rs526896, rs961014, rs11880992, rs7466269, rs2974438, rs16860216, rs6439168, rs2856321, rs11684404, rs6696239, rs6894139, rs1401795, rs4337252, rs9993613, rs6714546, rs181338, rs11144688, rs17450430, rs1681630, rs817300, rs862034, rs9217, rs1815314, rs4974480, rs606452, rs9328445, rs7043114, rs994533, rs1950500, rs9835332, rs1923367, rs1233032701, rs2573640, rs2573640 07, rs10948222, rs7980687, rs310421, rs6902771, rs7716219, rs897080, rs2806561, rs3807931, rs2280470, rs10780910, rs6600365, rs4620037, rs4803468, rs9880211, rs7154721, rs3020418, rs422421, rs12474201, rs12209223, rs7027110, rs1582931, rs7731703, rs12347744, rs509035, rs584828, rs7733195, rs7534365, rs12470505, rs2074977, rs12639764, rs2278483, rs1047014, rs6955948, rs6577717, rs1659127, rs10990303, rs6974574, rs7551732, rs227724, rs301901, rs13177718, rs6920372, rs11648796, rs2888877, rs2421992, rs822531, rs2597513, rs1325596, rs648831, rs2413143, rs7971536, rs291979, rs4072910, rs6879260, rs2390151, rs3958122, rs12779328, rs2237886, rs6540834, rs2956605, rs2028067, rs17511102, rs16859517, rs2425163, rs10152591, rs564914, rs7899004, rs763318, rs4652773, rs425277, rs39623, rs975210, rs8052560, rs2013265, rs7605699, rs1233627, rs2338115, rs10119624, rs2306694, rs4246302, rs6761041, rs4812586, rs1415701, rs8180991, rs8073371, rs955748, rs170rs258165 42, rs3790086, rs3782089, rs4332428, rs2302580, rs891088, rs1329393, rs7126398, rs11867479, rs11633371, rs10883563, rs318095, rs749052, rs9816693, rs7319045, rs8006657, rs1562975, rs2377058, rs6903448, rs10843390, rs2857693, rs2834442, rs4601530, rs1265097, rs7853235, rs13088462, rs6594336, rs4428898, rs7561273, rs6457374, rs3767627, rs10767838, rs12204421, rs2070776, rs16895130, rs6485978, rs632124, rs7112925, rs17792664, rs3923086, rs1550162, rs12882130, rs11221442, rs1935157, rs757081, rs11880124, rs17391694, rs1599473, rs1405212, rs17603945, rs17721822, rs4640244, rs3014219, rs991946, rs3885668, rs6733349, rs12411277, rs2305833, rs6441170, rs6921207, rs7517682, rs1257763, rs1326023, rs12344396, rs389663, rs9456307, rs7568069, rs1753637, rs2072153, rs12904334, rs3809790, rs9889755, rs7177711, rs9404952, rs2211866, rs6694089, rs11659752, rs2300921, rs1864439, rs1190545, rs1980850, rs4246079, rs9766, rs3812591, rs26868, rs1809889, rs10877030, rs1658351, rs2811594, rs9409082, rs17807185, rs3812040, rs17163588, rs7567288, rs26024, rs11687941, rs34651, rs11599750, rs6899744, rs10131337, rs989393, rs540652, rs2123731, rs711245, rs13078528, rs2687950, rs3957165, rs1529701, rs10863936, rs11152213, rs6751657, rs316618, rs12120956, rs12855, rs4686904, rs3812423, rs10880969, rs4834927, rs10790381, rs6845999, rs12987566, rs16834765, rs2631676, rs17369123, rs354196, rs7567851, rs2378870, rs12323101, rs1546391, rs6919534, rs2510396, rs12125882, rs3828760, rs2781373, rs7273787, rs12926008, rs2257011, rs33852, rs902143, rs17032525, rs10794175, rs11047239, rs6988484, rs17806888, rs212524, rs6949739, rs4901537, rs8103068, rs8102380, rs12186664, rs1625895, rs9443804, rs8017130, rs7659107, rs1742829, rs2240919, rs4656220, rs780094, rs11745439, rs6838153, rs111753472471, rs1117599224 0326, rs13006748, rs932445, rs568610, rs4320932, rs1996422, rs7069985, rs4425077, rs2662027, rs4239020, rs17574650, rs479744, rs6561319, rs3739707, rs1341278, rs2072268, rs11677466, rs2145357, rs3129254, rs2306596, rs6420435, rs7834383, rs7727731, rs17349981, rs7985356, rs13393800, rs12458127, rs165189, rs4868126, rs1036477, rs2149163, rs4802134, rs10152739, rs567401, rs8067165, rs3763631, rs10495098, rs12435366, rs4953951, rs17088184, rs32855, rs4357716, rs6085662, rs2509133, rs7774834, rs12693589, rs2044124, rs8058684, rs429433, rs17122659, rs2298265, rs7823327, rs12055154, rs11107062, rs9858528, rs2166898, rs12119525, rs6962887, rs2735469, rs12153391, rs1113765, rs4875421, rs17038954, rs9395264, rs9977276, rs8097893, rs12820411, rs17264185, rs6999671, rs11855014, rs1348002, rs915506, rs4725061, rs738288, rs956796, rs4883972, rs6061231, rs2763273, rs4624820, rs11618507, rs3791673, rs1533269, rs929637, rs16939034, rs1552173, rs2117563, rs217181, rs7712162, rs642914643 24, rs10283100, rs497273, rs960006, rs2219320, rs12519505, rs9309101, rs2345835, rs10997979, rs8103992, rs6971575, rs4325879, rs1461503, rs11612228, rs782930, rs867245, rs2679184, rs11750568, rs13133465, rs4141885, rs9825951, rs2682587, rs2326458, rs6691924, rs6137287, rs2057291, rs7261425, rs4326884, rs1861908, rs6658763, rs3802758, rs8042424, rs17783015, rs1244981, rs11783655, rs11156098, rs12863103, rs10779751, rs761391, rs9841435, rs7253628, rs16994718, rs11799609, rs4843367, rs17499117, rs2164968, rs12533079, rs926438, rs6544089, rs17181956, rs2120335, rs17250196, rs129963, rs731874, rs9291926, rs1797625, rs6952113, rs6754426, rs1409156, rs7544462, rs2961830, rs2715094, rs13150868, rs6584575, rs2596831, rs11616380, rs1478610, rs11634405, rs1053996, rs209918, rs10492364, rs2099745, rs3927536, rs1614303, rs2014467, rs2238300, rs992157, rs199515, rs7259684, rs1055144, rs4605213, rs2046158, rs4350272, rs7654571, rs11722554, rs11640018, rs4344931, rs4895801, rs10401193, rs2748483, rs13388725, rs3116168, rs2915404, rs3817428, rs12871822, rs958225, rs273945, rs11661645, rs13183624, rs4713902, rs894343, rs6887276, rs11624136, rs10083886, rs5757318, rs10460566, rs6446315, rs820848, rs2343240, rs2633761, rs870183, rs2531992, rs11835818, rs11708412, rs10059761, rs7782764, rs1171615, rs12597498, rs12329133, rs1004202, rs3818416, rs6563199, rs16964211, rs12137162, rs13416119, rs2224538, rs8117259, rs2275325, rs10744956, rs10759774, rs6813055, rs163071, rs300039, rs11683207, rs10817960, rs11057552, rs953199, rs16968242, rs6020202, rs3132297, rs1576900, rs833706, rs703985, rs12615742, rs2451948, rs2888893, rs3748394, rs2188177, rs10140101, rs11714558, rs2058092, rs10766065, rs1945237, rs7299326, rs996743, rs2164747, rs11100790, rs11861084, rs999599, rs11616067, rs888403, rs1966913 0972, rs10048625, rs7170986, rs6596075, rs17330192, rs10972628, rs11198820, rs6511689, rs10962832, rs12454567, rs749234, rs17659078, rs4973429, rs2023693, rs1368380, rs6911389, rs8073177, rs17387330, rs11867943, rs11090631, rs6080830, rs14062, rs4243206, rs2247870, rs13113518, rs11950938, rs486359, rs1420023, rs17777628, rs11245515, rs8069300, rs12621643, rs17410035, rs7646824, rs6462432, rs6746356, rs1040941, rs4785393, rs6504389, rs1007358, rs4767473, rs7633464, rs2175513, rs936339, rs12914466, rs17075869, rs12513181, rs3169906, rs6688100, rs9327705, rs6829680, rs8028843, rs10995319, rs2059877, rs9405356, rs17113369, rs2167645, rs7097701, rs2272566, rs4746769, rs2815379, rs4674354, rs2034172, rs1014987, rs12669267, rs12731056, rs12228415, rs3026499, rs1544196, rs6794009, rs6762606, rs7162825, rs868489, rs11244750, rs11642612, rs17140875, rs2829941, rs2337143, rs11779459, rs1321666, rs6571772, rs12144094, rs4256170, rs3915129, rs7033940, rs7334755, rs833152, rs481268645, rs1199745 190423, rs10820814, rs9929889, rs11236294, rs7743622, rs11731978, rs1346490, rs7284476, rs2737220, rs7007200, rs1571892

RECURSOS ADICIONALES:
Cómo tu altura afecta tu salud
¿Por qué los holandeses son tan altos?

ACTUALIZACIÓN SEMANAL: 17 de enero de 2020