TÍTULO DO ESTUDO: Definindo o papel da variação comum na arquitetura genômica e biológica da altura do homem adulto
TÍTULO DO ESTUDO: Identificação de todo o genoma de 687 variantes associadas à altura.
VISÃO GERAL: Nos últimos 150 anos, a altura média do ser humano aumentou cerca de 10 centímetros. Embora fatores ambientais como a nutrição tenham uma forte influência no crescimento do corpo humano, está claro que a altura é uma característica altamente hereditária. Na verdade, acredita-se que até 80% da altura de uma pessoa seja geneticamente determinada! No entanto, a altura é uma característica muito complexa, influenciada por muitas variantes do genoma. Para identificar variantes genéticas associadas à altura, este estudo examinou mais de 250.000 indivíduos de ascendência europeia. Os pesquisadores descobriram 697 variantes genéticas associadas à altura. Juntas, essas variantes explicam ~ 16% das diferenças de altura observadas entre as pessoas. Algumas das variantes identificadas estão próximas de genes que estão envolvidos no desenvolvimento de ossos e cartilagens.
VOCÊ SABIA? A partir dos 40 anos, muitas pessoas começam a perder altura. Isso pode ser devido a vários fatores, como compressão da coluna vertebral relacionada à idade e distúrbios como osteoporose. Exercícios e nutrição saudável (incluindo muito cálcio) podem ajudar a manter ossos e músculos fortes e limitar a perda de altura. [FONTE ]
RESULTADOS DE AMOSTRA: Saiba mais sobre o Nebula Research Library .
VARIANTES ANALISADAS: rs724016, rs7692995, rs3791679, rs8756, rs143384, rs798497, rs3760318, rs806794, rs4896582, rs720390, rs4369779, rs3814333, rs3825199, rs12214804, rs552707, rs2079795, rs1155939, rs9292468, rs10859567, rs9392918, rs17556750, rs314263, rs1074683, rs4733724, rs7701414, rs3811958, rs2284746, rs42039, rs1036821, rs9428104, rs7870753, rs7652177, rs2093210, rs12538407, rs5742915, rs9650315, rs2289195, rs3118905, rs1884897, rs9967417, rs991967, rs3800461, rs2871865, rs4986172, rs1367226, rs11049611, rs1812175, rs4548838, rs4735677, rs1535466, rs16942341, rs7033487, rs10748128, rs10958476, rs7849585, rs4448343, rs2854207, rs526896, rs961014, rs11880992, rs7466269, rs2974438, rs16860216, rs6439168, rs2856321, rs11684404, rs6696239, rs6894139, rs1401795, rs4337252, rs9993613, rs6714546, rs181338, rs11144688, rs17450430, rs1681630, rs817300, rs862034, rs9217, rs1815314, rs4974480, rs606452, rs9328445, rs7043114, rs994533, rs1950500, rs9835332, rs192337767, rs12330370725, rs25770725, rs25770725, rs25736725, rs25736725, rs257337257 rs257367257032270370725, rs25733725, rs25736725, rs25736725. 07, rs10948222, rs7980687, rs310421, rs6902771, rs7716219, rs897080, rs2806561, rs3807931, rs2280470, rs10780910, rs6600365, rs4620037, rs4803468, rs9880211, rs7154721, rs3020418, rs422421, rs12474201, rs12209223, rs7027110, rs1582931, rs7731703, rs12347744, rs509035, rs584828, rs7733195, rs7534365, rs12470505, rs2074977, rs12639764, rs2278483, rs1047014, rs6955948, rs6577717, rs1659127, rs10990303, rs6974574, rs7551732, rs227724, rs301901, rs13177718, rs6920372, rs11648796, rs2888877, rs2421992, rs822531, rs2597513, rs1325596, rs648831, rs2413143, rs7971536, rs291979, rs4072910, rs6879260, rs2390151, rs3958122, rs12779328, rs2237886, rs6540834, rs2956605, rs2028067, rs17511102, rs16859517, rs2425163, rs10152591, rs564914, rs7899004, rs763318, rs4652773, rs425277, rs39623, rs975210, rs8052560, rs2013265, rs7605699, rs1233627, rs2338115, rs10119624, rs2306694, rs4246302, rs6761041, rs4812586, rs1415701, rs8180991, rs8073371, rs955748, rs17081935, rs7745166, rs4273857, rs2581830, rs71625 42, rs3790086, rs3782089, rs4332428, rs2302580, rs891088, rs1329393, rs7126398, rs11867479, rs11633371, rs10883563, rs318095, rs749052, rs9816693, rs7319045, rs8006657, rs1562975, rs2377058, rs6903448, rs10843390, rs2857693, rs2834442, rs4601530, rs1265097, rs7853235, rs13088462, rs6594336, rs4428898, rs7561273, rs6457374, rs3767627, rs10767838, rs12204421, rs2070776, rs16895130, rs6485978, rs632124, rs7112925, rs17792664, rs3923086, rs1550162, rs12882130, rs11221442, rs1935157, rs757081, rs11880124, rs17391694, rs1599473, rs1405212, rs17603945, rs17721822, rs4640244, rs3014219, rs991946, rs3885668, rs6733349, rs12411277, rs2305833, rs6441170, rs6921207, rs7517682, rs1257763, rs1326023, rs12344396, rs389663, rs9456307, rs7568069, rs1753637, rs2072153, rs12904334, rs3809790, rs9889755, rs7177711, rs9404952, rs2211866, rs6694089, rs11659752, rs2300921, rs1864439, rs1190545, rs1980850, rs4246079, rs9766, rs3812591, rs26868, rs1809889, rs10877030, rs1658351, rs2811594, rs9409082, rs17807185, rs3812040, rs17163588, rs7567288, rs26024, rs11687941, rs34651, rs11599750, rs6899744, rs10131337, rs989393, rs540652, rs2123731, rs711245, rs13078528, rs2687950, rs3957165, rs1529701, rs10863936, rs11152213, rs6751657, rs316618, rs12120956, rs12855, rs4686904, rs3812423, rs10880969, rs4834927, rs10790381, rs6845999, rs12987566, rs16834765, rs2631676, rs17369123, rs354196, rs7567851, rs2378870, rs12323101, rs1546391, rs6919534, rs2510396, rs12125882, rs3828760, rs2781373, rs7273787, rs12926008, rs2257011, rs33852, rs902143, rs17032525, rs10794175, rs11047239, rs6988484, rs17806888, rs212524, rs6949739, rs4901537, rs8103068, rs8102380, rs12186664, rs1625895, rs9443804, rs8017130, rs7659107, rs1742829, rs2240919, rs4656220, rs780094, rs11745439, rs683824130, rs7659107, rs1742829, rs2240919, rs4656220, rs780094, rs11745439, rs683824153, rs1117532499271 rs9434723, rs9434723, rs94344992, rs9434723, rs94344992, rs94347238344992, rs9434723, rs9434834271 0326, rs13006748, rs932445, rs568610, rs4320932, rs1996422, rs7069985, rs4425077, rs2662027, rs4239020, rs17574650, rs479744, rs6561319, rs3739707, rs1341278, rs2072268, rs11677466, rs2145357, rs3129254, rs2306596, rs6420435, rs7834383, rs7727731, rs17349981, rs7985356, rs13393800, rs12458127, rs165189, rs4868126, rs1036477, rs2149163, rs4802134, rs10152739, rs567401, rs8067165, rs3763631, rs10495098, rs12435366, rs4953951, rs17088184, rs32855, rs4357716, rs6085662, rs2509133, rs7774834, rs12693589, rs2044124, rs8058684, rs429433, rs17122659, rs2298265, rs7823327, rs12055154, rs11107062, rs9858528, rs2166898, rs12119525, rs6962887, rs2735469, rs12153391, rs1113765, rs4875421, rs17038954, rs9395264, rs9977276, rs8097893, rs12820411, rs17264185, rs6999671, rs11855014, rs1348002, rs915506, rs4725061, rs738288, rs956796, rs4883972, rs6061231, rs2763273, rs4624820, rs11618507, rs3791673, rs1533269, rs929637, rs16939034, rs1552173, rs2117563, rs217181, rs71235143, rs641864143, rs64176414 24, rs10283100, rs497273, rs960006, rs2219320, rs12519505, rs9309101, rs2345835, rs10997979, rs8103992, rs6971575, rs4325879, rs1461503, rs11612228, rs782930, rs867245, rs2679184, rs11750568, rs13133465, rs4141885, rs9825951, rs2682587, rs2326458, rs6691924, rs6137287, rs2057291, rs7261425, rs4326884, rs1861908, rs6658763, rs3802758, rs8042424, rs17783015, rs1244981, rs11783655, rs11156098, rs12863103, rs10779751, rs761391, rs9841435, rs7253628, rs16994718, rs11799609, rs4843367, rs17499117, rs2164968, rs12533079, rs926438, rs6544089, rs17181956, rs2120335, rs17250196, rs129963, rs731874, rs9291926, rs1797625, rs6952113, rs6754426, rs1409156, rs7544462, rs2961830, rs2715094, rs13150868, rs6584575, rs2596831, rs11616380, rs1478610, rs11634405, rs1053996, rs209918, rs10492364, rs2099745, rs3927536, rs1614303, rs2014467, rs2238300, rs992157, rs199515, rs7259684, rs1055144, rs4605213, rs2046158, rs4350272, rs7654571, rs11722554, rs11640018, rs4344931, rs4895801, rs10401193, rs2748483, rs13388725, rs3116168, rs2915404, rs3817428, rs12871822, rs958225, rs273945, rs11661645, rs13183624, rs4713902, rs894343, rs6887276, rs11624136, rs10083886, rs5757318, rs10460566, rs6446315, rs820848, rs2343240, rs2633761, rs870183, rs2531992, rs11835818, rs11708412, rs10059761, rs7782764, rs1171615, rs12597498, rs12329133, rs1004202, rs3818416, rs6563199, rs16964211, rs12137162, rs13416119, rs2224538, rs8117259, rs2275325, rs10744956, rs10759774, rs6813055, rs163071, rs300039, rs11683207, rs10817960, rs11057552, rs953199, rs16968242, rs6020202, rs3132297, rs1576900, rs833706, rs703985, rs12615742, rs2451948, rs2888893, rs3748394, rs2188177, rs10140101, rs11714558, rs2058092, rs10766065, rs1945237, rs7299326, rs996743, rs2164747, rs11100790, rs11861084, rs999599, rs11616067, rs88375403, rs1966913, rs1966913 0972, rs10048625, rs7170986, rs6596075, rs17330192, rs10972628, rs11198820, rs6511689, rs10962832, rs12454567, rs749234, rs17659078, rs4973429, rs2023693, rs1368380, rs6911389, rs8073177, rs17387330, rs11867943, rs11090631, rs6080830, rs14062, rs4243206, rs2247870, rs13113518, rs11950938, rs486359, rs1420023, rs17777628, rs11245515, rs8069300, rs12621643, rs17410035, rs7646824, rs6462432, rs6746356, rs1040941, rs4785393, rs6504389, rs1007358, rs4767473, rs7633464, rs2175513, rs936339, rs12914466, rs17075869, rs12513181, rs3169906, rs6688100, rs9327705, rs6829680, rs8028843, rs10995319, rs2059877, rs9405356, rs17113369, rs2167645, rs7097701, rs2272566, rs4746769, rs2815379, rs4674354, rs2034172, rs1014987, rs12669267, rs12731056, rs12228415, rs3026499, rs1544196, rs6794009, rs6762606, rs7162825, rs868489, rs11244750, rs11642612, rs17140875, rs2829941, rs2337143, rs11779459, rs1321666, rs6571772, rs12144094, rs4256170, rs3915129, rs7033940, rs7334755, rs833156, rs114868734, rs114868734, rs114868734, 190423, rs10820814, rs9929889, rs11236294, rs7743622, rs11731978, rs1346490, rs7284476, rs2737220, rs7007200, rs1571892
RECURSOS ADICIONAIS:
Como sua altura afeta sua saúde
Por que os holandeses são tão altos?
ATUALIZAÇÃO SEMANAL: 17 de janeiro de 2020
