SUMMARY: Discovery of 28 novel genomic regions associated with breast cancer risk.
OVERVIEW: Breast cancer is the second most commonly diagnosed cancer in the United States. Much research has been done to find genetic variants associated with predisposition to breast cancer. However, most studies have been conducted in women of European ancestry, potentially missing breast cancer-associated variants that are less common in Europeans. This genome-wide association study combined genomic data from over 310,000 women of Asian and European descent and identified 28 novel variants associated with breast cancer risk. The study also confirmed over 100 previously identified genetic variants and found differences in genetic risk for breast cancer based on race.
DID YOU KNOW? Lifestyle changes can reduce the risk of breast cancer, even for women with a genetic predisposition to the disease. Some ways to lower the risk include consuming less alcohol, not smoking, controlling weight, and being physically active. [SOURCE]
SAMPLE RESULTS: Learn more about the Nebula Research Library.
ANALYZED VARIANTS: rs2981578 rs4784227 rs4442975 rs75915166 rs62355902 rs10941679 rs2046210 rs7297051 rs4973768 rs13281615 rs11249433 rs676256 rs10995201 rs1292011 rs34005590 rs17356907 rs999737 rs704010 rs1432679 rs45631563 rs2787486 rs6001930 rs16857609 rs4808801 rs13329835 rs2747652 rs10822013 rs6828523 rs10816625 rs9693444 rs2236007 rs4849887 rs17817449 rs1830298 rs6472903 rs13365225 rs616488 rs3215401 rs2823093 rs10759243 rs3817198 rs10069690 rs12422552 rs11977670 rs2290203 rs7072776 rs2943559 rs6762644 rs11814448 rs12628403 rs7107217 rs2992756 rs13294895 rs10474352 rs12493607 rs1011970 rs6796502 rs527616 rs1436904 rs28539243 rs34207738 rs11820646 rs17268829 rs2588809 rs3760982 rs204247 rs12048493 rs738321 rs10760444 rs6507583 rs1895062 rs941764 rs7904519 rs4593472 rs11199914 rs58847541 rs71559437 rs7707921 rs6569648 rs13267382 rs6597981 rs2016394 rs6964587 rs58058861 rs12546444 rs3903072 rs9485372 rs2965183 rs117618124 rs514192 rs6815814 rs720475 rs11075995 rs745570 rs6122906 rs6725517 rs76535198 rs12710696 rs73006998 rs35418111 rs17350191 rs4496150 rs12207986 rs11627032 rs4971059 rs35951924 rs2432539 rs71338792 rs10022462 rs9833888 rs1707302 rs17529111 rs2594714 rs10838267 rs67958007 rs8027365 rs4562056 rs8176636 rs113577745 rs7529522 rs1550623 rs146699004 rs6882649 rs1053338 rs77528541 rs16992204 rs12481286 rs11552449 rs6562760 rs9790517 rs11780156 rs6940159 rs6555134 rs1353747 rs2758598 rs72906468 rs2901157 rs11117758 rs12405132 rs3790585 rs10820600 rs116095464 rs855596 rs11281251 rs34331122 rs66823261 rs28512361 rs6756513 rs17426269 rs11944638 rs4233486 rs7765429 rs4951011 rs7768862 rs2223621 rs9316500 rs6596100 rs17156577 rs144145984 rs142360995 rs78588049 rs12479355 rs6805189 rs11947923 rs2849506 rs541079479 rs75004998 rs206966
ADDITIONAL RESOURCES:
Breast cancer (Video)
Mayo Clinic
WEEKLY UPDATE: March 30, 2020
