RESUMEN: Identificación de 258 variantes genéticas asociadas al factor de resistencia corneal.
VISIÓN GENERAL: La córnea es una «ventana» en forma de cúpula que cubre la parte frontal del ojo. Sirve tanto para proteger el ojo como para enfocar la luz para ayudarnos a ver. El daño a la córnea puede ser perjudicial para la vista, por lo que los médicos suelen utilizar una serie de métricas para medir la salud de la córnea. Una métrica es el factor de resistencia corneal, que mide la capacidad de resistencia total de la córnea. Un factor de resistencia corneal bajo se ha relacionado previamente con el glaucoma y otros trastornos del ojo. Este estudio de asociación de todo el genoma de más de 100.000 individuos de ascendencia europea buscó identificar variantes correlacionadas con el factor de resistencia corneal. El estudio encontró 258 variantes genéticas relacionadas con el factor de resistencia corneal. Muchas de las variantes asociadas con el factor de resistencia corneal también se relacionaron con la histéresis corneal, otra medida clave de la salud de la córnea que se examinó en este estudio.
¿SABÍAS? Para prevenir lesiones en la córnea, es muy recomendable usar anteojos de seguridad al realizar tareas domésticas, como usar un taladro o rociar pesticidas. [SOURCE]
RESULTADOS DE LA MUESTRA: Más información sobre el Biblioteca de investigación de nebulosa .
VARIANTES ASOCIADAS AL FACTOR DE RESISTENCIA: rs76210128, rs7635832, rs28425635, rs142493024, rs12686184, rs72755233, rs11659764, rs11616662, rs74948688, rs77542162, rs7722242, rs139657047, rs12493217, rs6792542, rs139498917, rs56009602, rs121908120, rs72620820, rs2393728, rs7863424, rs448203, rs471064, rs908839, rs8070232, rs2797575, rs1200108, rs12913547, rs6415788, rs150629672, rs1042917, rs75828199, rs11789898, rs2645775, rs4582532, rs7936322, rs4656744, rs2325812, rs79552011, rs6910919, rs11774662, rs12150284, rs62257174, rs7025044, rs4641686, rs11594610, rs12526513, rs3132302, rs943423, rs2875238, rs10814543, rs13108668, rs2980046, rs11077857, rs10071507, rs9510275, rs10817467, rs62279163, rs62014489, rs17665178, rs3740685, rs7524924, rs2109019, rs116713089, rs34869, rs2468511, rs8016138, rs11917483, rs10922476, rs10758571, rs12498681, rs75995975, rs1931656, rs11014595, rs6816503, rs10138009, rs35351529, rs62292473, rs187977459, rs58671886, rs66613683, rs2745950, rs544072714, rs6437582, rs12939159, rs66756859, rs10871335, rs 534975221, rs2035835, rs11689201, rs1794824, rs1772570, rs1573019, rs7403354, rs7919525, rs13018808, rs13071684, rs66560819, rs3782473, rs1344672, rs6501742, rs2950790, rs12193050, rs58933977, rs2505507, rs34372952, rs11602544, rs11772848, rs1042499, rs10124941, rs17819228, rs256869, rs4846306, rs115040818, rs249768, rs6874844, rs75529319, rs4646785, rs41310169, rs62289359, rs1113483, rs663044, rs882855, rs67239293, rs61301974, rs11857536, rs712097, rs1206035, rs7282723, rs6113029, rs9669278, rs4561781, rs2143109, rs6726007, rs78036526, rs10170879, rs3904683, rs840464, rs17089329, rs3775840, rs9844666, rs4846476, rs236940, rs6072289, rs4938174, rs13089362, rs8072109, rs12731820, rs7903474, rs61162043, rs61528732, rs62269315, rs9364323, rs10492232, rs10510110, rs3810027, rs9285863, rs73224432, rs1580697, rs7394259, rs180976308, rs4578552, rs2237421, rs78253835, rs4653159, rs12686780, rs13297186, rs144596877, rs12309229, rs62075722, rs3890958, rs41281862, rs9688830, rs16856870, rs4077168 , Rs1451018, rs73181764, rs4790881, rs6676809, rs1366689, rs6749785, rs11245342, rs1469024, rs6715589, rs13073544, rs1499894, rs1844594, rs10151339, rs72843943, rs7623659, rs139002703, rs1414154, rs4819855, rs117801489, rs56114706, rs807037, rs58627364, rs11688492, rs11499034, rs28368296 , rs114797817, rs2032423, rs10865493, rs1956213, rs1445844, rs2806681, rs141621919, rs2616418, rs215545, rs2348477, rs13138854, rs12790261, rs2301742, rs17006525, rs76667725, rs16893327, rs4827893, rs141773782, rs10045442, rs2167972, rs2256606, rs117693113, rs116899497, rs224979, rs12448432 , rs10853015, rs6725266, rs116998555, rs13141170, rs2160726, rs7886690, rs8068844, rs113542380, rs393091, rs7319674, rs141951483, rs12354975, rs149879035, rs10010325, rs4794213, rs1113231, rs11730582, rs10172196, rs17182988, rs183759316, rs4345115, rs10901294, rs74454622, rs77583146, rs868949 , rs1991161, rs8041717, rs151190321, rs2286936, rs13208672, rs8071654, rs142662688, rs2836484, rs154001
RECURSOS ADICIONALES:
El sistema visual: cómo funcionan tus ojos (Video)
¿Qué es la córnea?
USTED TAMBIÉN PODRÍA ESTAR INTERESADO EN:
Espesor corneal (Choquet, 2020)
Adelgazamiento de la córnea: queratocono (McComish, 2019)
Histéresis corneal (Simcoe, 2020)
ACTUALIZACIÓN SEMANAL: 27 de agosto de 2020
