Inflammatory protein level (Hillary, 2020)

STUDY TITLE: Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults

SUMMARY: Identification of 16 genetic variants associated with the presence of inflammatory proteins in the blood.

OVERVIEW: Inflammation is a response of the immune system to an infection or injury. It is caused by a release of inflammatory proteins that attract immune cells to fight the infection and increase blood flow to promote healing. However, sometimes these inflammation-promoting signals can occur and persist even when they aren’t needed and cause damage to the body. This study looked at the levels of inflammatory proteins in the blood and found 16 associated genetic variants. These variants explained up-to 45% of the variance in these levels. The study also linked some of the inflammatory proteins to specific diseases including Crohn’s disease, high blood pressure, and Alzheimer’s disease.

DID YOU KNOW? Chronic inflammation can be reduced by an anti-inflammatory diet. This includes eating foods high in omega-3 fats, antioxidants, probiotics, and fiber and avoiding foods that are high in trans fats, saturated fats, and omega-6 fats. [SOURCE]

SAMPLE RESULTS: Learn more about the Nebula Research Library.

inflammatory protein sample results

INFLAMMATORY PROTEIN LEVEL-ASSOCIATED VARIANTS: rs3138036, rs12075, rs2032887, rs2272128, rs11700291, rs2229092, rs6138139, rs1458038, rs6603134, rs10045431, rs11230563, rs485186, rs10005565, rs2247526, rs425535, rs3136618

Chronic inflammation (Video)
Understanding acute and chronic inflammation

Inflammation Markers in the Blood (Ligthart, 2018)
Crohn’s disease (Franke, 2010)
Alzheimer’s Disease (Kunkle, 2019)

WEEKLY UPDATE: July 21, 2020