STUDY TITLE: Genome-wide association studies and Mendelian randomization analyses for leisure sedentary behaviours
SUMMARY: Identification of 4 genetic variants associated with driving for leisure.
OVERVIEW: Leisure sedentary behaviors, like watching Netflix and playing Animal Crossing, sure can be fun! In fact, the average adult in the United Kingdom spends an average of 5 hours per day on activities like this. However, research suggests that long periods of sedentary behaviors could increase an individual’s risk for conditions like coronary artery disease. This study aimed to identify genomic regions associated with leisure sedentary behaviors, in particular, television watching, computer use, and driving, and examine whether there are links to coronary artery disease. To this end, the researchers examined genomic data from over 420,000 individuals of European ancestry from the UK Biobank. For leisure driving, the researchers identified 4 associated genomic regions. Further analysis showed that an increase in time spent driving increased the risk of coronary artery disease significantly.
DID YOU KNOW? Just 30 minutes of driving time each day increases your risk of obesity, poor sleep quality, and negative effects on your psychology. Whenever possible, try to take public transportation because it involves more walking and standing than driving does. [SOURCE]
SAMPLE RESULTS: Learn more about the Nebula Research Library.
DRIVING-ASSOCIATED VARIANTS: rs1198575, rs6012558, rs10186876, rs4765541
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WEEKLY UPDATE: May 5, 2020