SUMMARY: Identification of 5 risk variants associated with the development of gliomas.
OVERVIEW: Glial cells are found in the brain, spine, and other parts of the nervous system. The function of the glial cells is to protect and support the nervous system. Gliomas are a form of cancer that result from the uncontrolled growth of glial cells. To identify risk variants for this disease, this study examined the genetic information of over 11,000 individuals of Western European ancestry. Five variants associated with this type of cancer were discovered. The variants were linked to genes that play a role in maintaining genomic stability. Together, the identified variants may explain between 7 and 14% of the heritable risk of developing this cancer.
DID YOU KNOW? Age, exposure to radiation and family history are the main risk factors for developing gliomas. [SOURCE]
SAMPLE RESULTS: Learn more about the Nebula Research Library.
STUDY-ASSOCIATED VARIANTS: rs4295627, rs2736100, rs4977756, rs6010620, rs498872
WEEKLY UPDATE: March 9, 2020