Atrial Fibrillation (Okubo, 2020)

Nebula Genomics DNA Report for Atrial Fibrillation

Is atrial fibrillation (AF) genetic? We created a DNA report based on a study that attempted to answer this question. Below you can see a SAMPLE DNA report. To get your personalized DNA report, purchase our Whole Genome Sequencing!

STUDY TITLE: Predicting Atrial Fibrillation using a Combination of Genetic Risk Score and Clinical Risk Factors

SUMMARY: Prediction of atrial fibrillation risk using 5 genetic variants.

OVERVIEW:  Atrial fibrillation (AFib) is an irregular heartbeat that is much faster than normal. It occurs when the two upper chambers of the heart beat out of sync with the lower chambers. This typically causes weakness and shortness of breath. This study sought to combine genetic and clinical factors to predict the risk of AFib in over 1000 individuals of Japanese descent. Confirming previous research, the researchers identified 5 genetic variants associated with AFib. The study determined a 4.92-fold difference in AFib risk between the highest and lowest polygenic scores that were calculated based on these variants. The risk estimate became more accurate if clinical factors were considered as well.

DID YOU KNOW? The latest iterations of the Apple Watch can detect AFib. [SOURCE]

SAMPLE RESULTS: Learn more about the Nebula Research Library.

Sample report on atrial fibrillation
Sample variants on atrial fibrillation
To learn more about how Nebula Genomics reports genetic variants in the table above, check out the Nebula Research Library Tutorial.

Looking for more information on heart health? You can start by reading our full article on heart disease. Plus, check out our other posts in the Nebula Research Library!