SUMMARY: Identification of multiple novel genetic variants that are associated with an increased risk of experiencing insomnia.
DESCRIPTION: Sleep plays a critical role in maintaining physical and mental health. Insomnia, characterized by difficulty falling asleep or staying asleep, is one of the most common sleeping disorders. It is also one of the most common mental disorders and a major risk factor for depression. This study gathered genetic data from 113,006 individuals of European ancestry and identified novel genetic variants. In particular, variants in two genes were significantly associated with the condition: MEIS1 and SCFD2. The MEIS1 gene has been linked by other studies to sleep disturbance. The study also analyzed each sex individually and discovered multiple variants in the WDR27 gene that are associated with the condition in males. Finally, strong positive genetic correlations were identified between insomnia and multiple psychiatric disorders, including anxiety, depression and, neuroticism.
DID YOU KNOW? Refraining from the use of electronic devices such as phones and computers an hour before bed may make it easier to fall asleep. Reading and meditating are excellent substitutes![SOURCE]
SAMPLE RESULTS: Learn more about the Nebula Research Library.
INSOMNIA-ASSOCIATED VARIANTS: rs113851554, rs574753165
WEEKLY UPDATE: July 23, 2019