GeneTrait Laboratories review – The best pharmacogenetics?

GeneTrait Laboratories Review Summary

GeneTrait Laboratories is a clinical genetics company that focuses on pharmacogenetics. Learn more in our GeneTrait Laboratories review!

Fiyin Ebemidayo, B.S.

genetrait laboratories logo


While there are no customer reviews online, the company notes that it processes over 40,000 samples per year, suggesting it is well received. The price depends on the patient’s insurance. The company offers several options focusing on different conditions, not just mental health.


7 Facts from our GeneTrait Laboratories Review

  1. Location: Columbia, MO
  2. Products: Genetic panels for pharmacogenetic testing
  3. Cost: Not available online
  4. Sample collection: Cheek swab
  5. Turnaround time: 3-5 days
  6. Raw data download: No
  7. Alternative Products: Nebula Genomics offers 30X Whole Genome Sequencing that decodes 100% of your DNA and gives reports on diet and much more!

This review is written with the intent to be as unbiased as possible. However, it represents the opinion of an individual reviewer and is therefore subjective. Furthermore, at Nebula Genomics we seek to educate the public about the benefits of Whole Genome Sequencing. Information about our Whole Genome Sequencing DNA test is therefore incorporated into the review.

May 9, 2023

Pros and Cons


  • Various tests for focused pharmacogenetics
  • Easy to read report for physicians
  • Forensic level testing at parent company for a 99.9999% accuracy


  • Must order and collect sample during a doctor’s appointment
  • Cost depends on insurance


GeneTrait Laboratories is a PTC Laboratories, Inc. division specializing in pharmacogenetic testing services. The company was founded in 2009 and has since been committed to advancing personalized medicine through genetic testing. The parent company, PTC Laboratories, Inc. was founded in 1996 as a DNA testing company and continues to process more than 40,000 samples per year. 

GeneTrait Laboratories’ goal is to help healthcare providers make better-informed patient care decisions. For this purpose, the company’s services help identify genetic variations that may impact an individual’s medication response, allowing physicians to make more effective personalized medication choices with fewer side effects.

GeneTrait Laboratories homepage
GeneTrait Laboratories homepage

With over two decades of genetic testing experience, GeneTrait Laboratories provides pharmacogenetic testing services to assist physicians in understanding which medications may work best for their patients based on their genetics. Furthermore, this service can help eliminate the expensive, time-consuming, and painful trial-and-error process of prescribing medication. 

GeneTrait Laboratories pharmacogenetic testing evaluates medications related to mental health, pain management, cardiology, and others. Markedly, it uses over 60 genetic locations to develop a genetic profile for one person, with a forensic approach that provides an accuracy level of 99.9999%. 

The laboratory is CLIA-compliant and also holds accreditations from multiple organizations. GeneTrait Laboratories’ staff chiefly consists of leaders in the genetic testing community, including Dr. Judith Miles, M.D., Ph.D., who serves as the Medical Director.

Are you interested in a test that decodes 100% of your DNA in addition to the few genes for pharmacogenetics? Nebula Genomics offers Whole Genome Sequencing! This is a complete DNA test that decodes all 20,000 genes and regulatory genomic regions. Click here to learn more!

The Science Behind GeneTrait Laboratories

GeneTrait Laboratories analyzes a patient’s DNA to identify genetic variations that can influence their response to medication. This information then provides personalized medication management recommendations to the patient’s physician.

The genetic variations analyzed can affect various factors related to medication response such as how quickly a medication is metabolized, how effective it is at treating a particular condition, and whether it is likely to cause side effects. 

Specifically considering medication metabolism genetic testing may indicate whether a patient needs a higher or lower dose.

The testing process involves analyzing specific genes influencing medication response, using techniques such as PCR (polymerase chain reaction) and sequencing. The results are then analyzed by trained genetic counselors and pharmacists, who provide personalized medication management recommendations based on the patient’s genetic profile.

Review of GeneTrait Laboratories Products

GeneTrait Laboratories, a genetic testing service provided by PTC Laboratories, offers several types of pharmacogenetic tests.

TestGenes testedMetabolism/risk factors
Pain management6opiates, NSAIDs, methotrexate, and tricyclic antidepressants
Cardiac11antiplatelet, antiarrhythmics, ARBs, statins, NSAIDs, plus elevated risk of heart disease, thrombosis and other cardiac and stroke related conditions
Psychotropic6anti anxiety, SSRI/SNRIs, antipsychotics, benzodiazepines, and tricyclic antidepressants, plus elevated risk of hyperhomocysteinemia
Surgery8antiplatelet, opiates, and NSAIDs, plus elevated risk of thrombosis and hyperhomocysteinemia
OB/GYN8antiplatelet, opiates, NSAIDs, and tricyclic antidepressants, plus elevated risk of thrombosis and hyperhomocysteinemia
Anti-ADHD6many common medications related to attention-deficit/hyperactivity disorder, plus elevated risk of hyperhomocysteinemia

Patients can also request a Full Panel, which includes the psychotropic, pain management, cardiac, and surgery panels.

Taking a GeneTrait Laboratories Test

Whereas samples for many genetic tests can be collected at home, a patient’s physician must order a pharmacogenetic test. Patients have their sample collected at the doctor’s office, which then ships it to the lab. Analysis is performed within 3-5 business days.

Finally, the ordering physician will receive the results and consult with the patient at the next visit.

Review of GeneTrait Laboratories Cost

The testing costs are not provided on the website. Therefore, patients who are interested in the panels should contact the company directly. Medicare, most medicaid, and most private insurance companies will cover the test. However, patients are encouraged to reach out to their insurance provider to determine their responsibility.

Review of a GeneTrait Laboratories Report

The GeneTrait Laboratories report is provided through MedTrait® Laboratory Report for medication metabolism and risk factor assessment. As has been noted, the company provides the results directly to the ordering physician and they will discuss it with their patient.

MedTrait considers several variables including pharmacogenetics, drug interactions, duplicate therapy awareness, demographics, and lifestyle factors while providing clinical guidance for prescribing physicians.

In brief, the report is divided into three sections:

  • Highlights on the first page: At-a-glance information on what the physician needs to know
  • Details
  • References
GeneTrait Laboratories details page sample
GeneTrait Laboratories details page sample

While the highlights page provides only the most vital prescribing information, the additional pages discuss details related to all medications the patient currently takes.

The score takes into account drug interactions, genetics, and lifestyle.

GeneTrait Laboratories sample report grid
GeneTrait Laboratories sample report grid

Then, the report interprets the results and arranges medication in an easy-to-read grid. The four quadrants represent higher risk, lower risk, higher benefit, and lower benefit.

Review of GeneTrait Laboratories Privacy Policy

GeneTraits Laboratories does not have a privacy policy on its website. However, the policy provided by its parent company, PTC Laboratories indicates that it does not sell or share information with any third parties. 

It also claims to only collect information that it will use to provide the services requested.

Other GeneTrait Laboratories Review

GeneTrait Laboratories does not have reviews from third parties such as Amazon, Trustpilot, and the Better Business Bureau (BBB). They also remain unrated on However, their Facebook reviews page shows a few 4.6 star ratings, although most are close to ten years old.

Nebula Genomics

GeneTrait Laboratories offers a range of options for pharmacogenetics testing. This specific field of genetics focuses on a patient’s predisposed reactions to medicactions. Much of the research is based on whether medications can cause certain side effects in some predisposed individuals and how well or poorly they metabolize medications. 

On the other hand, Nebula Genomics offers whole genome sequencing, providing a comprehensive view of an individual’s genetic makeup. Nebula is not a pharmacogenetics company. Instead, customers can receive the test kit at home and collect and send back their own sample.

Nebula provides a comprehensive DNA test highlighting predispositions related to health, disease, traits, and more. With 30x Whole-Genome Sequencing, we sequence 100% of your DNA to get to the root cause of every biological inclination. The test is also incredibly accurate and includes other additions, including ancestry reporting and genome exploration tools. Additionally, regularly updated reports ensure that you will not miss the latest genetic research. 

Nebula is not a diagnostic test, but the results are of the highest quality and can be used in consultation with health care professionals.

For only $299 or less, customers will get access to their entire genome, allowing them to continue to ask more questions as more research is conducted.

GeneTrait Laboratories vs. Nebula Genomics

GeneTrait LaboratoriesNebula Genomics
Testing methodCheek swabSaliva sample
Sample collectionAt a doctor’s officeAt-home
ReportsPharmacogenetics for a range of specialtiesGenetic predispositions covering health, disease, traits, and more
Ancestry reportingNoDeep ancestry reporting with the complete Y chromosome and mtDNA sequencing
Data uploadNoYes
CounselingNoNo but data is of the highest quality and can be used by physicians, and genetic counselors
CostN/A – may be covered by insurance$0, $99, $299

Did you like our GeneTrait Laboratories review? You can read more reviews on our blog and check out our complete guide to the best DNA test kit and other home tests.

Other companies

If you are interested in more pharmacogenetic options you may want to check out:

  • 24Genetics (various tests for health, ancestry, sports, skin, pharmacogenomics, WES, and WGS)
  • ClarityX DNA (pharmacogenetics for mental health and other conditions)
  • GeneSight (clinical genomic test for psychotropics)
  • Genomind (pharmacogenomic testing for mental health treatment)
  • Incite Health (pharmacogenetics for mental health treatments)
  • myDNA (personalized fitness, diet, and medication plans)
  • Veritas Genetics (disease risks, carrier screenings, and pharmacogenetics)

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