Item: <strong>24Genetics Review Summary</strong>
Rating: 4
Author: Fiyin Ebemidayo, B.S.

24Genetics Review Summary

24Genetics offers a series of DNA tests to help patients understand their health and predisposition for disease. Learn more in our 24Genetics review!

Fiyin Ebemidayo, B.S.

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Summary

24Genetics offers a number of options to analyze your health, from Sports specific DNA testing to whole genome sequencing. The reports are comprehensive, with up to 250 pages of information. However, prices are often higher than those of other DNA testing companies, especially for whole genome sequencing.

7 Facts from our 24Genetics Review

Location: Madrid, Spain
Products: 24Genetics offers DNA testing for health, ancestry, pharmacogenomics, nutrigenetics, skincare, sport, and Whole Exome Sequencing. Customers can also upload raw DNA data from Ancestry.com, 23andMe, MyHeritage, FTDNA, and other sites
Ordering: Patients can order an at-home DNA kit and only need to collect a saliva sample
Consultation: Consultation services are not available
Data: Patients can download their health data from their registered online space
Cost: $149-$289
Complimentary products: Nebula Genomics (Whole Genome Sequencing that can be used in consultation with a medical professional)

This review is written with the intent to be as unbiased as possible. However, it represents the opinion of an individual reviewer and is therefore subjective. Furthermore, at Nebula Genomics we seek to educate the public about the benefits of Whole Genome Sequencing. Information about our Whole Genome Sequencing DNA test is therefore incorporated into the review.

November 15, 2023

7 Facts from our 24Genetics Review
Pros And Cons
- Pros
- Cons
Introduction
Review of the Science Behind 24Genetics
Taking a 24Genetics Test
Review of 24Genetics Products
Review of 24Genetics Cost
Review of 24Genetics Reports
Review of 24Genetics Privacy
Nebula Genomics
- Other companies

Pros And Cons

Pros

Uses well-known technology for better testing
Extensive options to choose from
Clients can read reports without the help of a doctor

Cons

Testing is narrow
Whole exome and whole genome sequencing are expensive
Genetic counseling is only available with the most expensive tests
No user reviews

Introduction

24Genetics is a personal genetic testing company that offers a series of DNA tests to help patients understand their health and predisposition for conditions, including those that can be passed on to children. The company’s health test analyzes 700,000 genetic markers covering over 200 diseases, dozens of genetic predispositions to medication, and much more regarding overall health.

24Genetics was founded in Madrid, Spain, in 2016. It started as a biotechnology start-up and now operates in over 100 countries, with a large presence in Europe. It’s also popular in the United States, with a couple of locations and a headquarters in Boston, Massachusetts.

This company, which specializes in direct-to-consumer genetic tests delivered to customers’ homes, takes pride in the NCBI’s recognition of its tests. Its DNA products include ancestry, health, nutrigenetics, pharmacogenomics, sports, and skin care tests. The company’s ancestry DNA test covers more than 400 geographical areas and is one of the most detailed on the market.

The company provides its service to patients directly with its at-home test kits, which are extremely easy to use. Results are usually delivered within 24 hours of customer samples being received at the lab. The PDF report is usually available within 3-8 weeks.

Did you know that by sequencing your whole genome, you can learn more about your risk for a wide range of diseases and conditions? This may help determine if additional services are right for you. Nebula Genomics offers affordable whole genome sequencing that decodes 100% of your genome. Click here to learn more!

Review of the Science Behind 24Genetics

24Genetics provides ancestry and health tests to help customers make better decisions about their healthcare. It states that it offers a complete genetic test in the form of its Health Test product (700,000 genetic markers) as well as options for whole exome sequencing (40 million markers) and whole genome sequencing (3 billion markers).

The company’s ancestry test can show patients their DNA percentage in more than 600 regions, making it one of the most comprehensive genetic testing companies, as many others lag behind with only up to 50 regions. The company’s standard health test can provide information on 700,000 genetic markers and over 200 diseases.

With its customized and unique Illumina technology, the company ensures that DNA tests are performed precisely for a very affordable price without compromising quality.

Taking a 24Genetics Test

Users order their DNA extraction kit online and register it on the site. They will provide their email address, to which the company will send the reports.

The company provides a video on its website on how to properly collect DNA samples (either saliva or swab method). The tutorial is easy to follow and is not different from the general sample collection process.

Once the customer collects the sample, they return it to the lab using the return shipping instructions provided with the kit.

Review of 24Genetics Products

24Genetics offers patients comprehensive testing and results with its wellness and ancestry testing. It provides various separate reports as well as an all-in-one testing option.

The company offers eight major products, each drawing patients closer to their DNA and how genes affect their lives, health, and personalities. The firm’s overall mission is to ensure that patients know more about themselves and their predisposition to certain types of diseases and health conditions.

The all-in-one test provides all eight reports with one saliva sample. Below is a list of the products the company offers.

DNA Health

This test is one of the most popular tests and is usually done to inform customers about their susceptibility to the most common diseases. Information includes genetic health risks, oncological mutations, carrier status, and genetic biological traits such as high cholesterol and triglyceride levels.

Ancestry

24Genetics compare its genetic data against a vast DNA database with genomic markers from many places around the world. It can help patients trace their ancestral history through several generations. It goes deeper than most genetic testing firms as it compares DNA from more than 1500+ regions.

Pharmacogenomics

With the pharmacogenomics test, 24Genetics provides information on customers’ predispositions to various medications. With this DNA analysis, it can determine whether a client is predisposed to a drug that might be toxic or simply ineffective, among many more options. With this example of personalized medicine, customers can work with their doctors, who can prescribe the most effective and safe medications.

Note: Not available in the United States.

Nutrigenetics

This genetic test helps customers assess the best diet and nutrients that must be added into their foods for healthy development and immune system health. 24Genetics studies patients’ genes and allows them to create a daily plan that ensures that they get the best meal. This can be based on genetic factors such as how your body reacts or doesn’t react to certain nutrients and which vitamins and minerals your body absorbs poorly.

DNA Sports

With this DNA sports test, 24Genetics provides the customer with a complete analysis of the fitness and exercise that fit their strength. The company helps customers design an appropriate training plan that brings out the best benefits of sports while reducing the potential for injury.

Skincare

24Genetics analyzes genetics’ influence on skin characteristics such as hydration, elasticity, and antioxidant capacity, which play a key role in the skin aging process. The firm cites the fact that genes are responsible for 60% of the aging process, and a good test will go a long way to helping patients know what kind of skincare limits the effects of aging.

Microbiota

With this test, customers can have the oral microbiota of their mouth sequenced and analyzed. The microbiota can inform customers about their risk for diseases such as cavities and periodontitis. It is also less closely related to other conditions such as cancer.

The company performs this sequencing in a separate laboratory from its DNA testing.

Whole Exome Sequencing

Note: This product is no longer available on the company website.

Through the exome, the protein-coding section of the genome, 24Genetics accesses 85% of all useful data about a patient’s health in terms of its genetics. Exome sequencing is performed only once in a lifetime, as it does not change.

According to the company, patients can get any of the reports mentioned above with this test, and your data file will be ready for future reports based on new scientific discoveries. These customers also receive a Personality and Traits report, a report on a gene or pathology of interest, and a telephone genetic counseling consultation.

Whole Genome Sequencing

Note: This product is no longer available on the company website.

This test sequences all 3.2 billion bases in the human genome and is the most comprehensive DNA testing kit available. The company uses 30x whole genome sequencing to provide a complete picture of the genome, including health and trait aspects. Customers receive all of the reports and advantages in the exome sequencing kit as well as two 15-minute genetic counseling sessions.

Review of 24Genetics Cost

The pricing and payment options for 24Genetics are based on the type of test ordered and generally increase with the amount of genome sequenced.

The pricing for the at-home test kits is shown below:

Health DNA: $199 (free ancestry)
Ancestry: $149
Ancestry from raw data: $49
Pharmacogenetics Plus DNA Test: $199
Nutrigenetics DNA: $199 (free ancestry)
Nutrigenetics from raw data: $69
DNA sports: $199 (free ancestry included)
DNA sports from raw data: $69
DNA skincare: $199 (free ancestry)
DNA skincare from raw data: $69
Microbiota: $199
All-in-one: $399

Review of 24Genetics Reports

24Genetics offers specific reports when customers order a DNA test. These reports are provided as PDFs via email. Former 24Genetics customers only have to note they need a kit code in the comments of the order.

Clients can interpret the reports themselves without the help of a doctor. However, if there is any confusion, clients could meet with a doctor to help them read the report. 24Genetics results are not for clinical use, and its reports are for research, information, and educational purposes only. Reports are available in English, German, French, Italian, Polish, and Spanish.

Sample reports for all of the company’s services are available on the website. Additional information and a summary of each major report are provided below.

Health Report

The Health report is thorough with over 250 pages for customers to review. It is divided into five sections: GWAS, Genetic Health Risk: mutations, Carrier status, Biomarkers, biometrics and traits, and Pharmacogenetics. For an overview, you can refer to the summary section, which lists the various genetic aspects or conditions tested for and uses a color-coded system to flag the results of interest.

After the summary, each genetic result is broken down in detail with the following information:

Pharmacogenomics, Nutrigenetics, Sports, and Skin reports

The Pharmacogenomics, Nutrigenetics, Sports, and Skin reports are organized in the same way as the Health Report. They are shorter (30-50 pages) since they focus more on certain aspects, like vitamin and mineral metabolism.

The Pharmacogenetics report describes how patients may respond to different medications, such as specific blood thinners and antidepressants. Nutrigenetics will tell you how predisposed you are to nutritional intakes such as how likely you are to have an appetite for carbohydrates and how well your body absorbs specific vitamins and minerals. The Sports report focuses on things like power, resistance, and aerobic capacity, while the Skin report will give information on things like dermal sensitivity and acne.