Onegevity review – Can AI-driven gut insights help you live healthier?

Onegevity Review Summary

Onegevity uses sequencing technology to identify your gut microbiome and provide health insights. Learn more in our Onegevity review!

Fiyin Ebemidayo

Onegevity testing kit


Onegevity is known for a reasonably priced gut microbiome test that is reviewed well by customers.


This review is written with the intent to be as unbiased as possible. However, it represents the opinion of an individual reviewer and is therefore subjective. Furthermore, at Nebula Genomics we seek to educate the public about the benefits of Whole Genome Sequencing. Information about our Whole Genome Sequencing DNA test is therefore incorporated into the review.

December 23, 2020

7 Facts from our Onegivity Review

  1. Location: New York City 
  2. Products: Onegevity is a leading health intelligence platform for wellness. They’re professionals in various health fields, including genetics, blood work, microbiome, and physiology
  3. Ordering: Tests can be ordered online through the Onegevity website
  4. Costs: $39 (Agebio) – $349 (Gutbio). Other products TBA
  5. Reports: The test report reveals information about your body system. It provides personalized recommendations by artificial intelligence. The recommendations include lifestyle, nutrition, and dietary supplementation
  6. Privacy: The link to the company’s privacy policy is on the website’s homepage. They are committed to protecting the privacy and security of your information
  7. Complementary Products: Nebula offers 30X Whole Genome Sequencing. We provide our customers and patients with advanced sequencing technology. Our kit reads out over 6,000,000,000 positions in your genome (~ 100%)

Onegevity Introduction

Onegevity is the leading health intelligence platform for wellness. They offer various at-home test kits that can allow people to examine their health status. The company also combines a multi omic artificial intelligence (AI) platform to provides patients with science-based, consumer-friendly, personalized health insights to living healthier. This machine learning will recommend a suitable lifestyle, personalized nutrition, and dietary supplements predicted to optimize an individual’s health.

The company employs experts in many health fields and health dimensions, including genetics, blood work, physiology, microbiome, etc. They are also up to date on new discoveries. 

Their interdisciplinary approach to problem-solving plus the adoption of artificial intelligence, medicine, and science allows them to offer suitable solutions for customers looking to improve health outcomes. With them, you’ll have an insightful picture of your health, and you’ll be empowered with precise interventions to take action. 

Paul Jacobson is the CEO and co-founder of Onegevity since 2018. He’s also the CEO of Thorne Research, health, wellness, and fitness company based in New York. He’s a member of the board of directors of Drawbridge Health and Co-Chair, Board of Directors of Progenics Pharmaceuticals, Inc. The scientific founders are Dr. Joel Dudley and Dr. Chris Mason. Dr. Dudley and Dr. Mason are pioneers in AI-based diagnostics.

Onegevity leverages partner company Thorne’s network of physicians so that they can offer convenient testing and powerful analytical tools to improve health. Their goal is to provide tools to improve preventative care and lower healthcare costs for their patients in the long term.

Onegevity Science

Once the company’s artificial intelligence AI platform activates your test, you’ll be asked to answer specific questions about your medication history, exercise routine, habitual diet, plus other essential factors that can affect your health, metabolism, hormone, and lifestyle. 

The company provides an at-home microbiome test (Gutbio) and integrates it with the information you provided. Advanced Whole-Genome Shotgun Sequencing identifies and counts all microorganisms in your gut, including gut bacteria, archaea, viruses, yeast, fungi, and parasites. The Gutbio test will be used to ‘map and track’ your health and compare your results to other customers. An easy to read report is provided based on AI-driven recommendations for lifestyle, nutrition, and dietary supplementation.

Additional options include the biological age test (Agebio) in which customers can upload existing Quest Diagnostics Lab blood work or the performance test (Performbio) which uses stool, blood testing, and saliva samples. The latter test is still in product development as of December 2020, but indicates that it will be coming soon, except in AK, LA, MD, NY, and NJ. 

Cutting edge metagenomic sequencing and artificial intelligence analyzes the data and provides you with personalized recommendations to live healthier. 

Onegevity Review

How to take a Gutbio Test

The first step to take Onegevity test is to order the kit online and have it delivered. Using this method, you will skip the stress of waiting rooms and lab visits. 

When you receive your test kit, you’ll be required to collect a small stool sample. You can do yourself from the comfort of your home. After the sample collection, you will mail it back to the company with pre-paid postage.

It’ll take about four weeks before you get your test result and recommendations online. When the AI-powered, medical professional reviewed results are ready, you’ll see them on the company’s website, and you can download them for yourself. In the report, you’ll find details of every microorganism found in your sample. 

You’ll also receive personalized supplement recommendations for diets and lifestyle habits. Following this recommendation will help to improve gut health and whole-body wellness. 

The Gutbio test
Onegevity Gutbio test

How to take an Agebio Test

Currently, customers only have the option to upload existing Quest Diagnostics Lab blood work. Onegevity will analyze 41 biomarkers from the Complete Metabolic Panel, the Complete Blood Count with Differential, Hemoglobin A1c, DHEA-s, or the Lipid Panel. You will receive detailed information on how your body is aging and personalized recommendations to help you reverse aging. 

On their website, the company notes that the ability to download a requisition form to take to a local Quest Lab for a draw is coming soon.

The Agebio test
Onegevity Agebio test

How to take a Performbio Test

This test is coming soon except in the states of AK, LA, MD, NY, and NJ. Customers will be required to take a small stool sample, 2 dried blood spot cards, and 2 saliva samples. This test will measure performance indicators such as energy, recovery, performance drive, gut metabolism, diversity, and inflammation biomarkers. This information will be integrated with sleep, stress, mood, training, and nutrition questionnaire data.

The Performbio test
Onegevity Performbio test

Onegevity Cost Reviews

There are about three different test kits available from Onegevity, each for various purposes. Individuals experiencing constipation or diarrhea, frequent heartburn, excessive gas, bloating, abdominal pain, or nausea or who have a family history of IBS or IBD will be interested in the Gutbio test, which sells for $349. This test will examine the microbiome in your gut, and provide a suitable recommendation for GI discomfort.

If you want to live healthier for longer, have a family history of disease risk, have underlying health conditions, or are just generally interested in public health issues, you should consider an Agebio kit. It will reveal your biological age, a number that describes how your body is aging and is separate from a person’s chronological age in years. 

This kit costs $39 to upload existing lab data. With it, the company suggests they can help you reverse your aging clock.

The Performbio test is coming soon. The company has not released a price as of December 2020.  

Onegevity Report Reviews

Onegevity reports use artificial intelligence to generate suitable personalized recommendations for individuals after identifying all the microorganisms causing a particular symptom in their test results, plus the answers provided to the questions on their website by the patient. Both patients and health care professionals can use the report. 

A Gutbio report contains 2 sections consisting of results and personalized recommendations:

Results include:

  • Inflammation risk (Did you know you can test inflammation markers at home? Learn more in our article about at home inflammation tests).
  • Constipation risk
  • Diarrhea risk
  • Diversity
  • Micronutrients
  • Probiotics
  • Pathogens
  • Keystone phyla
  • Community breakdown

Personalized recommendations for customized health routines: supplements, exercise, etc.

A personalized supplement recommendation
A personalized supplement recommendation

For the risk sections, results will include a score, an interpretation of the score, and the identity of the microorganisms present in your gut that went into calculating the score.

A sample Onegevity report
A constipation score in a personalized report

Other sections, such as the diversity section, will analyze your gut and compare your score to other customers.

A sample Onegevity report
A comparison score in a Onegevity report

More sections will provide information as to whether the amount of certain types of microorganisms and whether they are within an optimal range. 

The probiotics section of a sample Onegevity report
The probiotics section of a Onegevity report

Onegevity Privacy Review

Onegevity upholds the privacy of its patients. They treat all the information provided by patients on their website with all forms of confidentiality. You can find a full copy of their privacy review by clicking on the “privacy statement” link at the bottom of their homepage. 

A section of their privacy statement reads, “Onegevity Health, LLC (“Onegevity Health”), commits to safeguarding the privacy and security of the information entrusted to us from health-care practitioners, patients, and customers who use our websites (collectively the “Website”), any subdomains of such Websites or any related sites, applications or online services offered by Onegevity Health (collectively, the “Services”).”

Some other information you’ll find in the privacy statement section includes the “acceptance of privacy statement,” “what the privacy statement covers,” and “Automatically Collected Information and Anonymous Information.”

Other Onegevity Reviews

There are several Onegevity health reviews about this company and its products online. Most customers review the Gutbio test positively. You can take some time to read what people are saying about them on Twitter #Onegevity.

A Twitter review of Onegevity
A Twitter review of Onegevity

Onegevity in the News

In 2019, Onegevity announced that they acquired global licensing rights to Mount Sinai’s Lab100, a clinic and research lab that uses precision diagnostics.

Onegevity Pros and Cons


  • At-home testing
  • Easy sample collection
  • Easy to understand report
  • Suitable personalized recommendations based on gut microbiome


  • Some might find the stool sample uncomfortable
  • No raw DNA upload

Nebula Genomics

At Nebula Genomics, we decode 100% of your DNA using Whole Genome Sequencing. This is more than what other DNA tests like 23andMe and AncestryDNA decode. Therefore, we can provide the most comprehensive and reliable personalized recommendations for our patients. 

With Whole Genome Sequencing (WGS), we decode all 6.4 billion DNA base pairs in the human genome. It cost over $3 billion to sequence the first human; however, with us, you can get the same test for less than $300. 

Gut microbiome tests like Onegevity only provide a snapshot of one health issue, digestive health. Nebula Genomics can give you deep genetic information about these conditions, plus much more. With weekly updates and data exploration tools, you can analyze your own data on almost any health issue at any time. Since new discoveries are coming out all the time, you can continuously learn more about your DNA – instead of settling for a single report such as that offered by companies like Onegevity. 

OnegevityViomeNebula Genomics
Testing MethodBlood, stool, and salivaRNA from gut microbes (stool sample), human RNA (blood sample)30x Whole Genome Sequencing
ReportingMicroorganisms that may cause a particular digestive problem. Personalized recommendations, which include lifestyle, nutrition, and dietary supplementationGut microbes present, proprietary “health scores”Genetic predisposition
Ancestry ReportingNoNoDeep ancestry reporting with full Y chromosome and mtDNA sequencing
Options for raw DNA uploadNoNoYes
Focus on PrivacyYesNoYes (learn more)
Cost$39 / $349$149 / $349$0 – $299
Onegevity vs Viome vs Nebula Genomics

If you’re interested in at home lab tests, you may also be interested in:

  • Atlas Biomed (microbiome and nutrition recommendations)
  • Biohm (gut health, including bacteria and fungi)
  • Biomesight (gut testing and recommendations)
  • DayTwo (gut health, personalized recommendations for blood glucose optimization)
  • InsideTracker (biomarker health tests and optional DNA test)
  • Ixcela (blood test for gut health and personalized recommendations)
  • Kean Health (gut health, recommendations, plus a gene test with 100+ traits)
  • Psomagen (gut health and gene test)
  • Rootine (personalized supplement and vitamins based on DNA test)
  • Sun Genomics (gut microbiome testing and personalized probiotics for adults, children, and infants)
  • Thryve (personalized probiotics)
  • Verisana (hormone, gut, and STD tests plus many more)
  • Viome (gut health and microbiome testing)

You may also be interested in virtual health care such as that offered by Teladoc and Lemonaid Health!

Did you like our Onegevity review? You can read more reviews on our blog and check out our complete guide to the best DNA test kit and other home tests.