Stripe2be review – Can your DNA help diagnose rare disease?

Stripe2be Review Summary

Stripe2be is a global genetic testing company that focuses on diagnosing and treating rare diseases. Learn more in our Stripe2be review!

Fiyin Ebemidayo

Results
Price
Comprehensive

Summary

The company focuses on rare diseases and has experts in this area to advise them. Therefore, their results are expected to be trustworthy. The price is higher than similar genetic sequencing products and since the company only focuses on rare diseases, customers will miss out on the large remainder of their health.

3.8

7 Facts from our Stripe2be Review

  1. Location: Loughborough, Leicestershire, United Kingdom
  2. Products: A Dante Lab Company, Stripe2be offers a Whole Genome Sequencing test that analyses 100% of a person’s DNA. The tests carried out by this genetic lab firm include rare disease reports and pharmacogenomics. The company offers a home kit as well as genetic counseling.
  3. Cost: $588-$882
  4. Reports: The company offers test results based on whole-genome sequencing tests, increasing the chances of finding a diagnosis. The major focus of the test is to diagnose rare genetic diseases using A.I algorithms.  
  5. How it works: Users upload relevant information mostly concerning your ancestry and then order the Stripe2be 30X whole genome sequencing test kit. At checkout you can choose your turnaround time as either eight weeks ($882) or two weeks ($588). Register the kit, perform the test in three simple steps, and mail it to the designated address. A notification email will be sent on result availability at the estimated time frame.
  6. Raw Data Access: Stripe2be offers raw data access to its registered kit users. Once you perform the test, you can easily request your raw data, which will be available in any format: FASTQ, BAM, and VCF.
  7. Alternative Products: Nebula 30X Whole Genome Sequencing is an alternative whole genome sequencing service that decodes all the information on your genome. Nebula reads over six million positions on your genome to provide you with reliable results that can be used in consultation with a medical professional.

Stripe2be Introduction

Stripe2be is a global whole genome sequencing company that specializes in helping to diagnose and treat rare diseases. Using a patient centric and unbiased approach through its artificial intelligence (AI) platform, the company serves to provide a genetic solution for patients suffering from the uncertainty or misdiagnosis of rare diseases. The company is a subsidiary of Dante Labs

The name, Stripe2be, comes from the visualization of the DNA model, the double helix, that looks like stripes (the rungs of the ladder). Like zebras, the individual “stripes” in the DNA are what make an individual unique. Hence, the name and the zebra print on its products. 

Stripe2be testing kit
Stripe2be testing kit

While company operations are mainly carried out in their business unit in Loughborough of Charnwood, Leicestershire, they ship their at home products worldwide. While they mainly operate as an on-site laboratory for DNA tests, it carries a range of packages that include genetic counseling, Home kits registration, personalized reports, and users’ access to raw data.

Stripe2be stands out from most genetic firms because its operations have predominantly focused on diagnosing rare genetic diseases and providing support for those seeking guidance and treatment. Almost 80% of rare diseases have a genetic component. The company believes that genetic testing can help patients get diagnosed faster and have a better understanding of the origin of their condition, prompting quicker and more accurate treatment options. 

Another strength of the firm is its pharmacogenomic reports. These reports help users identify specific genetic variants that could influence how their body processes more than 120 medications. The management boasts of offering “the most complete” pharmacogenomic report their customers can use to build a personalized treatment plan.

Stripe2be has collaborations with other genetic-related firms and rare disease advocacy groups such as Epilepsy Sparks, Rare Genomics, and Dazzle4Real. These companies contribute significantly to the effectiveness of Stripe2be in helping users who seek to know whether a condition is genetic or not get complete comprehensive detail. 

The Science of Stripe2be

Stripe2be is a DNA genetic laboratory that provides Whole Genome Sequencing (WGS) in analyzing 100% of clients’ DNA. WGS analysis offers the most comprehensive, detailed type of genetic test available by decoding the entire genome whereas many other commercial genetic tests only decode about 0.2%. The company breaks down user WGS data into easy-to-understand reports. 

Democratizing of genomics data

Stripe2be believes in using WGS to democratize DNA data. This means giving users access to everything encoded in their genome. With this in mind, Stripe2be has developed proprietary technology and highly specialized laboratories with an international team of scientists, geneticists, and bioinformatics specialists. Their technology and ability to integrate sequencing and medical data provides more accurate and faster results worldwide. 

Reports provided by Stripe2be
Reports provided by Stripe2be

Stripe2be is not just all about providing reports on your genetic complexity, but goes more into diagnosing rare diseases. The more rare a disease is, the more complex its diagnosis, research, and pharmaceutical options will be. The company believes that with better and more accessible sequencing technology, patients and their doctors will be better able to break through this complexity and find appropriate treatments more efficiently. This is especially so when the diagnosis is on rare diseases and includes a broad diversity of symptoms and signs.

Stripe2be Review

Taking a Stripe2be test

Getting to use the kit is extremely easy, and you do not need any technical knowledge to perform. 

You will first sign up as a user and upload relevant information mostly concerning your ancestry. Click the “Get your test” menu and order the Stripe2be 30X whole genome sequencing test kit. There are two options available; The first test option will return your WGS results in 8 weeks while the second offers expedited results that take two weeks for you to get the test result.

How to take a Stripe2be test
How to take a Stripe2be test

Once you receive the test, register it. You will receive a unique code that allows you to access your results when available and perform subsequent activities. You can do this online or quickly activate your kit by scanning the QR code on the back of the box. Then, you will collect your saliva sample and mail to the designated address.

Depending on the kit offered, your result will be made available at the estimated time frame.

Review of Stripe2be reports

Specifically designed to diagnose rare genetic conditions, the Stripe2be test kit offers tests for conditions such as

  •  Epilepsy
  • Mental and behavioural illness
  •  Neurodegenerative conditions

The personalized reports are created with the assistance of AI interpretation software. According to the company, they break down the WGS data into 5 easier to read reports. These reports include:

Rare disease report

The company harmonizes A.I. algorithms and genomic data to help provide diagnoses for rare diseases. It also reduces waiting times previously needed for filtering and prioritizing variants.

Pharmacogenomic analysis

The company also learns clients’ personal genetic variants to know how they might influence their body processes over 120 medications. The platform also builds a personalized treatment plan with the complete Pharmacogenomic Report on the market.

Analyze all pathogenic variants

The company offers a complete variant analysis panel where you can find the answers to the cause of the insistent illness clients go through. Clients get to find answers to serious questions about their health and more.

Full raw data

With its developing science, the company uses the Whole Genome Sequencing Test to provide full raw data to clients on request, so they can make positive life changes that allow them to live healthier lives. The raw data is available in different formats such as FASTQ, BAM & VCF.

Genetic counseling

Once users receive their results, many still have questions as to how their genetic data should be used. The company offers genetic counseling to help users interpret their results and create clinical treatment plans.  You can request genetic counseling at any time after purchasing your test.

Genetic counseling available
Genetic counseling available

Each session lasts 1 hour for test result interpretation plus 15 minutes for questions and answers. Reports must be shared at least 2 weeks before the appointment. 

There is also the option to connect with accredited rare disease associations and advocacy groups. 

Review of Stripe2be cost

Stripe2be offers 30X WGS tests with reports that focus on rare genetic diseases.  

Compared to other WGS kits, Stripe2be prices are on the high side. The reason is most likely a result of their ability to test and diagnose rare conditions.

The at home kit costs are:

  •  Stripe2Be WGS 30X (2 Weeks) – $588
  • Stripe2Be WGS 30X (8 Weeks) – $882

The company offers two types of genetic counseling. A single general genetic counseling session costs $235 for a 75 minute session. Customers can also choose nutrigenomic counseling for $164 for a 75 minute session.

Review of Stripe2be Privacy

The company makes claims that your privacy is one of their core values. To do this, they perform all activity within the US or UK and are fully compliant with the General Data Protection Regulation (GDPR). They will collect personal information in order to process the service they offer. 

Their database is compiled on a Cloud on Amazon Web Services (AWS), which they claim provides the highest level of security. If you do not want your data saved, you can request it be deleted at any time by emailing hello@stripe2be.com.

Stripe2be in the News

A subset of Dante Labs, Stripe2be was released in July 2021 as a way to tackle Rare Disease Odysseys, the long search for a positive diagnosis, on a global scale. 

You can read their release statement on BioSpace.

Other Stripe2be Reviews

As of this writing, this service is only about 2 months old, which means that not many independent reviews are available online. 

Some discussion threads think the revamp is a marketing strategy to divert users away from some of the more negative reviews of the parent company, Dante Labs.

Users on reddit are starting discussions on the company, including what is included in the reports. Some new customers believe the reports will be similar to those offered by Dante Labs.

Read our review of Dante Labs here!

Stripe2be Pros and Cons

Pros

  • Uses 30X Whole Genome Sequencing for comprehensive coverage
  • Focuses on rare diseases, an area often overlooked 
  •  Performs unbiased, patient centric analysis with AI features
  • Offers genetic counseling
  • Access to raw data on request

Cons

  • The prices for its at home kits are higher than competitors
  • Only geared to rare diseases and not other health conditions
  • No ancestry analysis

Nebula Genomics

Like Stripe2be, Nebula Genomics offers 30X whole genome sequencing (WGS) to perform comprehensive DNA sequencing that unlocks the entire genome. Most importantly, Nebula focuses on more than rare diseases. With Nebula Genomics, users receive a DNA analysis with reports that explain your genetic risk for hundreds of conditions, from rare diseases like epilepsy, to common ailments such as high cholesterol, and even cancer.

While Nebula Genomics is not a diagnostic company, our whole genome sequencing data is of the highest quality and can be used by physicians and genetic counselors. Compared to true diagnostic companies like Stripe2be, Nebula offers the best value for your money. For $299 or less, you can have 100% of your genome sequenced and access to DNA exploration, which allows you to compare your unique genetics to new research for many health conditions. Compare this to the $588 for Stripe2be, which only focuses on rare diseases. 

With the Nebula Genomics Research Library, you can unlock reports on the most recent scientific research and continue to learn more about your genetic code throughout your lifetime!

Stripe2beNebula Genomics
Sample collectionSalivaSaliva
DNA testing methodWhole Genome Sequencing (30X coverage)Whole Genome Sequencing (30X coverage)
Ancestry testingNoIn-depth ancestry reporting with a full Y chromosome and mtDNA sequencing in collaboration with FTDNA
Raw DNA downloadYes (FASTQ, BAM, and VCF files)Yes (FASTQ, BAM, and VCF files)
Information providedOne report per every aspect tested with details, recommendations, and call to actionWeekly reports based on the latest research and data (learn more)
Cost$588-$882$0 – $299
Stripe2be vs Nebula Genomics

CENTOGENE and GeneDx are other diagnostic companies that specializes in rare diseases.

Other clinical diagnostic companies, many that include some panels are rare diseases, include:

Did you like our Stripe2be review? You can read more reviews on our blog and check out our complete guide to the best DNA test kit and other home tests.