Fitness Genes review – Can this DNA kit help you get fit?

Fitness Genes Review Summary

Fitness Genes is a DNA testing service that promises to help you find the right exercise method. Read more in our Fitness Genes review!

Nebula Genomics



Fitness Genes supports personalized fitness and weight loss goals through comprehensive reports and reasonable prices.


7 facts from our Fitness Genes Review

  1. Location: Bicester, Oxfordshire (Headquarters) and Beverly Hills, California
  2. Products: FitnessGenes testing kit and DNA data upload
  3. Reports: Fitness recommendations based on DNA data analysis
  4. DNA data access: Yes
  5. Privacy: Compliant with EU data protection laws
  6. Cost: $49 for data upload; up to $199 for DNA testing kits
  7. Alternatives: Nebula Genomics (free reporting for data uploadsthe most affordable whole genome sequencing)

This review is written with the intent to be as unbiased as possible. However, it represents the opinion of an individual reviewer and is therefore subjective. Furthermore, at Nebula Genomics we seek to educate the public about the benefits of Whole Genome Sequencing. Information about our Whole Genome Sequencing DNA test is therefore incorporated into the review.

April 11, 2022

Edited by Christina Swords, Ph.D.

Fitness Genes Pros and Cons


  • The cost is comparable with other genetic testing services
  • It provides in-depth fitness and nutrition information 
  • Users can download raw data
  • Extended support to help you meet your exercise and diet goals, including access to experts like nutritionists and personal trainers (at an extra cost) 


  • If you live outside the US, Canada, and the UK, you will have to pay extra to ship your test kit back to the lab
  • Does not provide DNA ancestry, genealogy, family tree, or last name origin information
  • No specific information about genetic diseases 

Fitness Genes Introduction

Fitness Genes (FitnessGenes) is a direct-to-consumer DNA testing company launched in 2013 by Dr. Samantha Decombel and Dr. Dan Reardon. The company analyses DNA to provide tailored workouts, nutrition plan-based programs, access to a genetic coaching team, and a supportive online community. Read more in our Fitness Genes review!

Did you know that most genetic tests like Fitness Genes decode only 0.02% of your DNA? Now, imagine if you can have access to 100% of your DNA!

That’s what Nebula Genomics has for you: Affordable Whole Genome Sequencing!

With this kind info, you can learn more about your ancestors, personalized tips on wellness, and tailored plans towards good health!

Click here to learn more!

How to Get Started

Let’s first briefly review Fitness Genes products.

Fitness Genes Free Account

The free Fitness Genes tier doesn’t provide a free genetic analysis. However, it educates you about the role of genetics in things like gut inflammation, vitamin absorption, obesity risk, and muscle growth.

Fitness Genes DNA Upload ($49)

First, let’s review the Fitness Genes DNA upload option. The service allows you to use DNA test results from 23andMe, AncestryDNA, Family Tree DNA, Living DNA, and MyHeritage.

After signing up and uploading your data, you’ll have access to notes based on your genetic traits, tailored recommendations on how to get fit and hold a nutritious diet, and personalized recipes. Additionally, you also get access to the members’ area.

Furthermore, you can purchase additional genetically-tailored training and nutrition plans to help you lose body fat and build muscle mass.  

Fitness Genes DNA Analysis ($199)

When the Fitness Genes DNA analysis kit arrives in your mailbox, you will provide a saliva sample and ship it back. The lab will extract the DNA from cells present in the saliva sample and analyze the genetic information to report on over 40 important genes for fitness and nutrition. 

The TrueTrait® algorithm will use your genetic results, lifestyle data, and fitness goals to give you personalized and actionable recommendations for optimal diet and exercise habits.

FitnessGenes offers DNA analysis with 4, 8, or 12 weeks detailed, personalized daily workout plans and nutrition plans (for $229, $259, and $289 respectively). You can download your raw DNA data, but whether this data is entirely compatible with third-party genetic data analysis is uncertain. 

Review of Fitness Genes Reporting

These are the genes analyzed by the Fitness Genes test. The website provides more details on each function and frequency of genotypes.

ACTN3 Speed, helps fast-twitch muscle
ACVR1BMuscle strength
ADRB2_1 & ADRB2_2Adrenaline signaling
AGTBlood pressure regulation
AKT1Aerobic exercise response
ALDH2Alcohol metabolism
AMPD1 Energy production
APOA2 Saturated fat intake
APOA5 Triglyceride levels
BDKRB2 Vascular function
CKM Muscle energy
CLOCKSleep cycle
CNTF Nerve activity
CYP1A2 Caffeine metabolism
HERC2 Eye color
HIF1A Response to low oxygen
IGF1 & IGF1_2 & IGFBP3 Regular growth/development
IL15RAMuscle volume
IL6 Inflammation and recovery
IL6R Regulating IL6 activity
LCTLactose tolerance
LPL HDL cholesterol levels
MC4R Overeating
MSTN & MSTNRAREHypertrophy / Unusual muscle size and strength
MTHFR gene & MTHFR_SNP2 Folate metabolism
MTR Homocysteine conversion
MTRRMethionine production
NMB Disinhibited eating
NOS3Blood flow
PGC1AAerobic capacity
PPARAFat burning
PPARGFat and carb processing
SHBG1 & SHBG2 Testosterone levels
SLC30A8Fasting glucose levels
UCP2 & UCP3Metabolism
VDR Vitamin D processing/activation (Did you know you can test for Vitamin D levels at home? Learn more in our article about vitamin D tests)
VDR_TaqResponse to vitamin D
VEGFA Blood vessel formation

This is what the report looks like:

Some of the genes analyzed by Fitness Genes.
Some of the genes analyzed by Fitness Genes

For each gene, you’ll get a genetic profile of the gene’s function, genotype, and advice. For example, the CLOCK gene affects the sleep cycle. So the DNA results may suggest that the user is a night owl. The company then advises on better sleep habits and exercise.

A detailed description of an analyzed gene
A detailed description of an analyzed gene
Description of the user's phenotype for an analyzed gene
Description of the user’s phenotype for an analyzed gene
Personalized Fitness Genes recommendations
Personalized Fitness Genes recommendations

Review of Fitness Genes Privacy

Is your data kept private?

The company states that it will not provide personal information or genetic data to third parties without permission. However, with your consent, Fitness Genes will retain the remainder of your DNA sample for up to 12 years for potential research and development. 

Fitness Genes will not store personal information along with the sample. You may opt-out of research and development anytime. However, even if the study produces commercial revenue, you will not be compensated. 

While you can withdraw your consent, your DNA cannot be removed if the study is already underway. The company will share your personal information with the government if required by law or if deemed necessary to prevent criminal acts.

Is Fitness Genes safe? 

Personal data is safeguarded according to UK and EU data protection laws. Data is encrypted during storage and during transport; this end-to-end AES encryption is the type used for online banking. 

Fitness Genes in the News

Fitness Genes has been covered by the Los Angeles Times, Forbes, and Men’s Journal, among others. In addition, the company teamed up with Gold’s Gym in July 2018 to launch DNA-based personal training programs.

Fitness Genes has also partnered with fitness expert and YouTube star Scott Herman to offer DNA analysis along with an 8-week muscle building plan. This plan includes a FitnessGenes results report, online support, and personalized training and nutrition Action Blueprint.

Other Fitness Genes Reviews

There are many sites where you can access Fitness Genes reviews and testimonials. For example, there are over 900 FitnessGenes reviews on Trustpilot, rating 4.5 out of 5 stars. On, over 300 people have given it an average rating of 5/5. 

On Facebook, Fitness Genes reviews have an average rating of 4.2 out of 5, based on opinions from more than 80 people. On Amazon, Fitness Genes reviews average 5 stars by five individuals. Fitness Genes reviews are also available on the company’s website. 

Nebula Genomics

The final section of our Fitness Genes review will compare it to Nebula Genomics and other DNA testing companies.

Nebula Genomics is different from genetic testing companies like Fitness Genes, 23andMe, and AncestryDNA. Nebula Genomics is focused on privacy, uses more advanced DNA testing technology, and provides you with more genetic data than most other DNA testing companies. 

What services are offered? 

Nebula Expand 

The Nebula expanded DNA report is free. All you need to do is upload your data from 23andMe or Ancestry!

Nebula Genomics uses a statistical technique called “imputation” to fill in gaps in regular DNA tests like Fitness Genes. Based on this expanded data, you’ll access a report on hundreds of genetic traits. 

Whole Genome Sequencing

Services like Fitness Genes, 23andMe, and Ancestry only read less than 0.1% of your genome.

On the other hand, Nebula Genomics uses full genome sequencing to decrypt 100% of your genome. You’ll also get access to the regularly updated Nebula Library and our genome exploration tools to search for specific genes or genetic variants in your genome. 

Privacy is a Priority

You shouldn’t have to place your privacy on the line for the chance to learn about your genome. Nebula Genomics is the first privacy-focused personal genomics service. 

Unlike companies like Fitness Genes, you maintain ownership of your genetic data. We connect you directly with potential third-party data buyers so that if you choose to share your genetic data, you can earn money. Read about our approach to DNA privacy here.

Here’s how Nebula Genomics 30x Whole Genome Sequencing compares to 23andMe, Ancestry, and Fitness Genes. 

23andMeAncestryDNAFitness GenesNebula Genomics
Produced data~600,000 positions in the genome~700,000 positions in the genome~650,000 positions in the genome~3,000,000,000 positions in the genome (whole genome DNA sequencing)
Nutrition and fitness coaching NoNoYesNo
Regular updates based on the latest discoveriesNo NoNew traits released, but not necessarily based on new researchYes (learn more)
Ancestry reportingYes, but based on relatively few genetic variantsYes, but requires sharing data with other Ancestry customersNoneDeep ancestry reporting with full Y chromosome and mtDNA sequencing
Privacy focusNoNoYesYes (learn more)
Cost$99 or $199$99 or $119$49 or $199 with the option to purchase extended plans$0, $99, $299

Other DNA testing services similar to Fitness Genes are:


  • DNAFit (in partnership with CircleDNA)
  • FoundMyFitness (one-time report or lifetime updates and other perks with subscription)
  • GeneFood (data upload and a personalized nutrition test)
  • Genopalate (data upload and DNA testing kit)
  • Nutrigenomix (personalized nutrition based on 70 variants)
  • Vitagene (diet and health)

General Fitness:

  • AthGene (30+ reports tailored to fitness, nutrition, and lifestyle)
  • Athletigen (free upload and basic report; additional tests and reports available at an additional cost)
  • Genomelink (fitness information)
  • (fitness app purchased separately)
  • Xcode Life (fitness and health report)

General Health:

There are a lot of great supplement companies out there that may help you lose weight and get healthy (you can read about many of them on our blog!) But be careful! There are also dangerous experimental drugs out there like SR9009 and RAD 140 that are not approved for human consumption.

Explore all our reviews and check out our complete guide to the best DNA test kit and other home tests! Or, if you need more information, you can read more about DNA diet tests!